iTrace和Pentacam及LOCSⅢ参数在晶状体混浊程度评估中的相关性

Correlations among parameters of iTrace,Pentacam and lens opacities classification systemⅢin lens opacity assessment

目的:分析iTrace视功能分析仪和Pentacam三维眼前节分析系统及晶状体混浊分级系统Ⅲ(LOCSⅢ)在年龄相关性白内障(ARC)患者晶状体混浊评估中的相关性。方法:前瞻性横断面研究。纳入2021-05/08本院眼科的ARC患者104例104眼。裂隙灯行LOCSⅢ分级;iTrace获取晶状体混浊地形图分级(OMG)和晶状体功能失调指数(DLI);Pentacam获取核分级(PNS)和Scheimpflug图像,ImageJ测量Scheimpflug图像各区域的累积光密度(IntDen)。SPSS 26.0分析参数正态性和相关性。结果:各参数除3mm范围IntDen和6mm范围后囊区IntDen外均正态分布。PNS与NC、NO均正相关(r=0.521、0.440,均P<0.01)。3mm范围IntDen与NC、NO均正相关(rs=0.459、0.450,均P<0.01)。3mm范围核区IntDen与NC、NO均正相关(r=0.539、0.543,均P<0.01)。3mm范围后囊区IntDen与NC、NO均负相关(r=-0.315、-0.321,均P<0.01)。6mm范围IntDen与NC、NO均正相关(r=0.321、0.288,均P<0.01)。3mm范围DLI与NC、NO、PSC均负相关(r=-0.257、-0.234、-0.282,均P<0.01)。6mm DLI与NC、NO、PSC均负相关(r=-0.247、-0.304、-0.227,均P<0.05)。3mm范围OMG与CC、PSC均正相关(r=0.268、0.333,均P<0.01)。6mm范围OMG与CC、PSC均正相关(r=0.275、0.245,均P<0.05)。3mm范围DLI与PNS、3mm范围核区IntDen均负相关(r=-0.217、-0.197,均P<0.05)。结论:三种晶状体混浊评价系统各有优势,将各参数结合可更客观地评价晶状体各区混浊,为临床提供参考。

·AIM:To analyze the correlations among parameters from iTrace visual function analyzer,Pentacam 3 D anterior segment analysis system and lens opacities classification system(LOCS)Ⅲin the assessment of lens opacity of age-related cataract(ARC)patients.·METHODS:A prospective cross-sectional study.A total of 104 ARC patients(104 eyes)in the department of ophthalmology of our hospital from May to August,2021 were included.The cataracts of patients were graded based on LOCSⅢusing a slit-lamp.Opacity map grade(OMG)and dysfunctional lens index(DLI)were obtained by iTrace.Pentacam nucleus staging(PNS)and Scheimpflug images of lenses were acquired by Pentacam.The regional integrated density(IntDen)of Scheimpflug images was obtained by ImageJ.The normality and correlations of parameters were analyzed by SPSS 26.0.·RESULTS:All the parameters were normally distributed except 3 mm IntDen and IntDen of 6 mm posterior subcapsular region.PNS positively correlated with nuclear color(NC)and nuclear opalescence(NO)(r=0.521,0.440,all P<0.01).The 3 mm IntDen positively correlated with NC and NO(rs=0.459,0.450,all P<0.01).IntDen of 3 mm nucleus region positively correlated with NC and NO(r=0.539,0.543,all P<0.01).IntDen of 3 mm posterior subcapsular region was negatively correlated with NC and NO(r=-0.315,-0.321,all P<0.01).6 mm IntDen positively correlated with NC and NO(r=0.321,0.288,all P<0.01).3 mm DLI negatively correlated with NC,NO,and posterior subcapsular cataract(PSC)(r=-0.257,-0.234,-0.282,all P<0.01).6 mm DLI negatively correlated with NC,NO,PSC(r=-0.247,-0.304,-0.227,all P<0.05).3 mm OMG positively correlated with CC and PSC(r=0.268,0.333,all P<0.01),and 6 mm OMG positively correlated with CC and PSC(r=0.275,0.245,all P<0.05).3 mm DLI negatively correlated with PNS and IntDen of 3 mm nucleus region(r=-0.217,-0.197,all P<0.05).·CONCLUSION:Each lens opacity assessment system had its own advantages.Taking all parameters into comprehensive consideration is conducive to objectively eraluate the opacity degree of each area of the lens and provide references for clinical work.