基于古今医案云平台挖掘中药治疗溃疡性结肠炎组方用药规律

Based on the Ancient and Modern Medical Records Cloud Platform to dig the Medication rules of Traditional Chinese Medicine in the treatment of ulcerative colitis

目的借助古今医案云平台挖掘中药治疗溃疡性结肠炎的组方用药规律。方法选取古今医案云平台中的现代医案库及名医医案库所收录的相关医案,对用药进行频次分析、属性分析、关联分析及复杂网络分析。结果共获得209个医案,包含319味中药,其中核心用药为黄连、木香、茯苓、白芍、甘草等;药性以温、平、寒为主,药味以苦、甘为主,药物归经以脾、胃、肝经为主。核心药对为木香-黄连等。核心处方是由白术、白芍、黄芩、木香、黄连、甘草、白头翁、茯苓、党参9味药组成。结论溃疡性结肠炎的中药治疗主要以四君子汤、香连丸为基础,配以清热解毒、凉血止痢等药物,从而标本兼治。

Objective The medical records collected on the Ancient and Modern Medical Record Cloud Platform were used to explore the medication rules of Traditional Chinese Medicine for the treatment of ulcerative colitis.Methods By selecting the medical cases of the modern medical database and medical cases of famous doctors in the ancient medical database on the cloud platform to analyze the frequency,attribution,association,and complex network of those medicines.Results A total of 209 medical records were obtained,including 319 Traditional Chinese Medicines,of which the core medicines were Rhizoma Coptidis,Radix Aucklandiae,Poria,Radix Paeoniae Alba,and Radix Glycyrrhizae.The properties of those medicines were warm,mild,and cold.The main taste is bitter and sweet,and most of them attibute to spleen,stomach,and liver meridians.The core pair medicine is Radix Aucklandiae-Rhizoma Coptidis.The core prescription was composed of nine herbs including Rhizoma Atractylodis Macrocephalae,Radix Paeoniae Alba,Radix Scutellariae,Radix Aucklandiae,Rhizoma Coptidis,Radix Glycyrrhizae,Radix Pulsatillae,Poria,and Radix Codonopsis.Conclusion The treatment of ulcerative colitis with Traditional Chinese Medicine mainly include Sijunzi Decoction and Xianglian Pill,accompanied with those medicines which could clear heat with detoxication function,cool the blood and stop diarrhea,By doing so,ulcerative colitis could be treated both in the surface and the root.