摘要
金黄色葡萄球菌(Staphylococcus aureus)是院内获得性感染的主要病原体之一,金黄色葡萄球菌会引起患者的严重感染,对患者的治疗和预后产生不良影响。现今临床预防和治疗金黄色葡萄球菌感染主要依赖抗生素。近年来,随着金黄色葡萄球菌耐药性的增强,万古霉素(Vancomycin)成为治疗其感染的最后一道抗生素防线。目前迫切需要探寻新的治疗方法来代替抗生素治疗。现归纳针对金黄色葡萄球菌耐药性的最新疗法,旨在为预防和治疗金黄色葡萄球菌感染提供新的思考。
Staphylococcus aureus, one of the most common etiological agents in hospital-acquired infections, can cause serious infections that threaten treatment and recovery. At present, clinical prevention and treatment of Staphylococcus aureus infection mainly rely on antibiotics. In recent years, vancomycin has become the last antibiotic line of defense against Staphylococcus aureus infection as drug resistance has increased. There is an urgent need to find new treatments to replace antibiotic treatment. This article will summarize the methods of treating Staphylococcus aureus infection in recent years in order to provide ideas for developing new therapeutics.
作者
唐丽(综述)
靳英丽(审校)
TANG Li;JIN Ying-li(Department of Pharmacology,College of Basic Medical Science,Jilin University,Changchun 130021,Jilin Province,China)
出处
《微生物学免疫学进展》
CAS
2022年第5期66-71,共6页
Progress In Microbiology and Immunology
基金
吉林大学“大学生创新创业训练计划”创新训练项目(S202110183547)。
关键词
金黄色葡萄球菌
耐药性
预防
生物膜
外排泵
溶血素
Staphylococcus aureus
Drug resistance
Prevention
Biofilm
Efflux pump
Hemolysin