音乐放松训练结合黄芪建中汤口服足浴对癌因性疲乏患者疲乏状态及生活质量的影响

Effects of music relaxation training combined with Huangqi Jianzhong Decoction oral administration and foot bathing on fatigue status and quality of life in patients with cancer related fatigue

目的探讨音乐放松训练结合黄芪建中汤口服足浴对癌因性疲乏(cancer related fatigue,CRF)患者疲乏状态及生活质量的影响。方法将符合入选标准的2019年1月-2020年10月张家口市妇幼保健院90例CRF患者,采用随机数字表法分为2组,每组45例。2组均给予健康及饮食宣教,对照组在此基础上给予音乐放松训练,观察组在对照组基础上结合黄芪建中汤口服足浴。2组均4周为1个疗程,共治疗3个疗程。分别于治疗前后进行中医证候评分,采用Piper疲乏量表(Piper Fatigue Score,PFS)评估患者的疲乏状态,Karnofsky功能状态评分评估患者生活质量,评价临床疗效。结果治疗结束后观察组43例、对照组42例进入疗效统计。观察组总有效率为83.72%(36/43)、对照组为64.29%(27/42),2组比较差异有统计学意义(χ^(2)=4.18,P=0.041)。观察组治疗后中医证候评分低于对照组(t=2.48,P=0.015),Karnofsky功能状态评分高于对照组(t=2.83,P=0.006),PFS量表中情感[(4.35±1.02)分比(5.03±1.01)分,t=3.09]、感觉[(4.31±1.06)分比(5.00±1.02)分,t=3.06]评分及总评分[(4.23±1.07)分比(4.87±1.10)分,t=2.72]均低于对照组(P<0.01)。结论音乐放松训练结合黄芪建中汤口服足浴可有效缓解CRF患者的疲乏状态,提高生活质量,疗效优于音乐放松训练。

Objective To explore the effect of music relaxation training combined with Huangqi Jianzhong Decoction oral administration and foot bath on fatigue status and quality of life in patients with cancer related fatigue.Methods A total of 90 patients with cancer related fatigue in our hospital from January 2019 to October 2020 were selected.The patients were divided into 2 groups by random number table method,with 45 in each group.Both groups were given health and diet education.The control group was given music relaxation training,and the observation group took Huangqi Jianzhong Decoction oral administration and foot bathing on the basis of the control group.Both groups have a course of treatment of 4 weeks,a total of 3 courses.The TCM syndrome scores were observed before and after treatment,and the Piper Fatigue Score(PFS)was used to evaluate fatigue status,and the Karnofsky functional state score was used to evaluate the quality of life of patients,evaluation of clinical efficacy.Results After treatment,43 patients in the observation group and 42 patients in the control group were analyzed.The total effective rate of the observation group was 83.72%(36/43),which was significantly higher than 64.29%(27/42)of the control group(χ^(2)=4.18,P=0.041).After treatment,the TCM syndrome scores in the observation group was significantly lower than that of the control group(t=2.48,P=0.015).After treatment,the Karnofsky functional state score in the observation group was significantly higher than that of the control group(t=2.83,P=0.006).After treatment,the emotion score(4.35±1.02 vs.5.03±1.01,t=3.09),feeling score(4.31±1.06 vs.5.00±1.02,t=3.06)and total score(4.23±1.07 vs.4.87±1.10,t=2.72)in the observation group were significantly lower than those in the control group(P<0.01).Conclusion Music relaxation training combined with Huangqi Jianzhong Decoction oral administration and foot bathing can alleviate the fatigue state of CRF patients and improve the quality of life.