摘要
鼻腔激发试验(NPT)是诱发鼻腔出现类似变应性鼻炎(AR)症状或症状加重的临床试验。用变应原进行的NPT是诊断AR的重要方法,但目前国内外尚没有统一的变应原使用标准、操作标准和结果判定标准。中国鼻病研究协作组(CRRCG)召集国内中青年鼻科和变态反应科专家,基于临床经验和循证医学证据制订了变应原NPT专家共识。本共识聚焦变应原NPT的适应证、禁忌证、变应原试剂标准、操作标准、阳性判定标准、检查前后注意事项等,为NPT的临床应用提供指导。
Nasal provocation test(NPT) with allergen is known as an important standard for the diagnosis of allergic rhinitis(AR). However, there is no unified allergen use standard, operation protocol and result judgement standard in the world. The China Rhinopathy Research Cooperation Group(CRRCG) convened young and middle-aged nasal experts in China to formulate an expert consensus on NPT with allergen based on clinical experience and medical evidences. This consensus focuses on the indications, contraindications, allergen reagent standards, operation standards, positive determination standards, precautions before and after test of NPT with allergen, and provides guidance for clinical application.
作者
王洪田
于睿莉
安云芳
刘锋
王天生
杨钦泰
陆美萍
邱前辉
王向东
陈建军
孟粹达
谢志海
孙悦奇
孟娟
曾明
许成利
王英
杨玉成
张维天
唐隽
杨艳莉
徐睿
喻国冻
石照辉
魏欣
叶惠平
孙亚男
余少卿
张天虹
雍军
杭伟
许元腾
许昱
谭国林
孙娜
洪海裕
杨贵
李幼瑾
叶菁
左可军
张立强
王学艳
李华斌
中国鼻病研究协作组
WANG Hongtian;YU Ruili;AN Yunfang;LIU Feng;WANG Tiansheng;YANG Qintai;LU Meiping;QIU Qianhui;WANG Xiangdong;CHEN Jianjun;MENG Cuida;XIE Zhihai;SUN Yueqi;MENG Juan;ZENG Ming;XU Chengli;WANG Ying;YANG Yucheng;ZHANG Weitian;TANG Jun;YANG Yanli;XU Rui;YU Guodong;SHI Zhaohui;WEI Xin;YE Huiping;SUN Yanan;YU Shaoqing;ZHANG Tianhong;YONG Jun;HANG Wei;XU Yuanteng;XU Yu;TAN Guolin;SUN Na;HONG Haiyu;YANG Gui;LI Youjin;YE Jing;ZUO Kejun;ZHANG Liqiang;WANG Xueyan;LI Huabin;Chinese Rhinopathy Research Cooperation Group(Department Allergy and Center of Allergy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;Department of Otolaryngology,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China;Department of Otolaryngology Head and Neck Surgery,West China Hospital,Sichuan University,Chengdu 610041,China;Department of Otolaryngology Head and Neck Surgery,Third Xiangya Hospital,Central South University,Changsha 410013,China;Department of Otolaryngology Head and Neck Surgery&Department of Allergy,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Otolaryngology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China;Department of Otolaryngology Head and Neck Surgery,Guangdong Provincial People’s Hospital,Guangzhou 510080,China;Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Department of Otolaryngology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Department of Otolaryngology Head and Neck Surgery,China-Japan Union Hospital of Jilin University,Changchun 130033,China;Department of Otolaryngology Head and Neck Surgery,Xiangya Hospital,Central South University,Changsha 410008,China;Department of Otolaryngology,the Seventh Affiliated Hospital of Sun Yat-sen University,Shenzhen 518170,China;Department of Otolaryngology,Head and Neck Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Department of Otolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Guangxi Medical University,Nanning 530007,China;Department of Rhinology,the First Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Otolaryngology Head and Neck Surgery,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China;Department of Otolaryngology Head and Neck Surgery,Sixth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China;Department of Otorhinolaryngology,Affiliated First People’s Hospital of Foshan City,Sun Yat-Sen University,Foshan 528000,China;Department of 1st Otolaryngology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China;Department of Otolaryngology,Otorhinolaryngology Hospital,the First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,China;Department of Otolaryngology,Guizhou Medical University,Guiyang 550001,China;Department of Rhinology&Skullbase Surgery,Longgang Otolaryngology Hospital,Shenzhen 518116,China;Department of Otolaryngology Head and Neck Surgery,Hainan General Hospital,Hainan Affiliated Hospital of Hainan Medical University,Hainan Province Hospital,Haikou 570311,China;Department of Otolaryngology,Guizhou Province Hospital,Guiyang 550002,China;Department of Otolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Department of Otolaryngology Head and Neck Surgery,Tongji Hospital,Tongji University School of Medicine,Shanghai 200065,China;Department of Otolaryngology Head and Neck Surgery,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Department of Otolaryngology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Department of Otolaryngology Head and Neck Surgery,Huanhu Hospital of Tianjin City,Tianjin 300350,China;Department of Otolaryngology Head and Neck Surgery,the First Affiliated Hospital of Fujian Medical University,Fuzhou 350004,China;Department of Otolaryngology Head and Neck Surgery,Renmin Hospital,Wuhan University,Wuhan 430060 China;Department of Otolaryngology,Huadong Hospital,Fudan University,Shanghai 200040,China;Department of Otolaryngology,the 5th Affiliated Hospital,Sun Yat-sen University,Zhuhai 519000,China;Department of Otolaryngology,the Central Hospital of Shenzhen Longgang District,Shenzhen 518116,China;Department of Otolaryngology,Shanghai Children’s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;Department of Otolaryngology Head and Neck Surgery,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China;Department of Otolaryngology,Qilu Hospital of Shandong University,Jinan 250012,China;Department of Otolaryngology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China;不详)
出处
《中国眼耳鼻喉科杂志》
2023年第1期1-10,共10页
Chinese Journal of Ophthalmology and Otorhinolaryngology
基金
国家自然科学基金杰出青年基金(81725004)
国家自然科学基金项目(81670901、81371074、81870706、81873689、81670906、81974140、82160210)
国家重点研发计划(2022YFC2504100)
北京市教委-北京市自然科学基金联合资助重点项目(KZ202110025030)
上海市科委优秀学科带头人项目(19XD4010000)
上海市耳鼻咽喉疾病临床中心重大专项(20MC920200)
广东省中医药局科研项目(20191063)
深圳市科技计划项目JCYJ(20210324121413037)。
关键词
鼻腔激发试验
变应原
变应性鼻炎
专家共识
Nasal provocation test
Allergen
Allergic rhinitis
Expert consensus
