链球菌中毒性休克综合征

Streptococcal toxic shock syndrome

链球菌中毒性休克综合征(STSS)是由A族链球菌(GAS)引起的一种发病突然、进展迅速、死亡率高的侵袭性感染疾病,随着抗菌药物的广泛应用,GAS感染的发病率虽已大幅降低,但由于STSS通常在其临床过程的早期阶段即引起休克和多器官衰竭,且临床症状非特异,早期识别、及时抗感染治疗和对症处理尤为关键,需引起临床医师的高度重视。

Streptococcal toxic shock syndrome(STSS)is a Group A Streptococcus(GAS)induced invasive infectious disease,which is characterized by abrupt onset and rapid progression with a high mortality rate.With the wide application of antimicrobial agents,the incidence of GAS infections has been substantially reduced.Nevertheless,STSS usually causes shock and multiple organ failure at the early stage of its clinical process,and the clinical symptoms are non-specific.Therefore,early identification,timely anti-infection and symptomatic treatment are particularly critical.Clinicians should pay high attention to the disease.