前置胎盘相关危险因素分析

Analysis of risk factors related to placenta previa

目的 探讨前置胎盘相关危险因素,提高孕产妇对前置胎盘的危险因素的认识。方法 回顾性分析2018年1月至2020年12月在郑州大学第一附属医院住院分娩的288例前置胎盘孕妇的临床资料,比较分析前置胎盘患者和正常孕产妇在年龄、受孕方式、胎儿数、孕次、产次、剖宫产次数、流产次数、流产方式和宫腔操作史、妊娠28周前彩超提示胎盘前置状态、合并妇科疾病等方面的差异。结果 单因素分析显示:年龄、孕次、产次、剖宫产次数、流产次数、人流/清宫次数、胎儿数量、妊娠28周前彩超、提示胎盘前置状态以及妊娠合并妇科疾病与前置胎盘存在相关(P<0.05),宫腔操作史、受孕方式在前置胎盘患者和正常孕产妇中差异无统计学意义;多因素logistic回归分析表明:妊娠28周之前彩超持续提示胎盘前置状态、流产次数是前置胎盘的危险因素。结论 流产次数是导致前置胎盘的主要危险因素;妊娠28周之前彩超持续提示胎盘前置状态是前置胎盘的一个临床征兆。

Objective To investigate the risk factors of Placenta Previa and to improve the understanding of the risk factors of Placenta Previa.Methods The clinical data of 288 pregnant women with placenta previa who delivered in the First Affiliated Hospital of Zhengzhou University from January 2018 to December 2020 were retrospectively analyzed, to compare and analyze the difference between placenta previa patients and normal parturients in age, mode of pregnancy, number of fetus, times of pregnancy, times of Cesarean section, times of abortion, times of abortion, ways of abortion and history of uterine cavity operation, color doppler ultrasound before 28 weeks of pregnancy to indicate the state of Placenta Previa, complicated with gynecological diseases, etc.Results Single factor analysis showed that age, pregnancy times, parturition times, times of caesarean section, times of abortion, times of abortion/curettage, number of fetuses, color Doppler ultrasound before 28 weeks’ gestation, placental previa, and pregnancy complicated with gynecological diseases were significantly associated with pregnancy, placenta previa was correlated(P<0.05). There was no significant difference in the history of uterine cavity operation and the mode of conception between the patients with placenta previa and normal pregnant women Multivariate logistic regression analysis showed that color Doppler sonography before 28 weeks of gestation consistently indicated that placenta previa and the number of miscarriages were the risk factors of placenta previa.Conclusion The number of induced abortion/purging and the history of uterine cavity operation were the main factors leading to placenta previa. Color doppler ultrasound before 28 weeks of gestation continuously suggests that Placenta Previa is a clinical sign of Placenta Previa.