孟鲁司特联合布地奈德治疗哮喘的疗效分析

Analysis of the Efficacy of Montelukast Combined with Budesonide in the Treatment of Asthma

目的:探讨孟鲁司特联合布地奈德治疗哮喘的效果。方法:选取2020年1-10月当阳市人民医院收治的76例支气管哮喘患者为研究对象,根据随机数字表法分为对照组与研究组,各38例。对照组给予常规药物治疗,研究组在对照组基础上给予孟鲁司特治疗,比较两组治疗效果、肺功能各项指标水平、症状缓解时间。结果:研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05);研究组第1 s用力呼气容积(FEV_(1))、FEV_(1)百分比、FEV_(1)/用力肺活量、6 min步行试验距离高于对照组,差异有统计学意义(P<0.05);研究组咳嗽、喘息及胸闷缓解时间短于对照组,差异有统计学意义(P<0.05)。结论:哮喘患者采用孟鲁司特联合布地奈德进行治疗,可有效控制临床症状,提高治疗效果,改善肺功能,促进患者早日康复,提高患者生活质量。

Objective:To investigate the efficacy of montelukast combined with budesonide in the treatment of asthma.Methods:Seventy-six patients with bronchial asthma admitted to Danyang People’s Hospital from January to October 2020 were selected for the study,and were divided into the control group and the study group according to the random number table method,with 38cases each.The control group was given conventional drug treatment,and the study group was given montelukast treatment on the basis of the control group,comparing the treatment effect,the level of each index of lung function,and the time of symptom relief between the two groups.Results:The total efficiency of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05);the 1st second expiratory volume(FEV_(1)),FEV_(1)percentage,1-second rate,and6 min walking test distance in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05);the relief time of cough,wheeze,and chest tightness in the study group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Treatment of asthma patients with montelukast combined with budesonide can effectively control clinical symptoms,improve treatment effect,improve lung function,promote early recovery and improve patients’quality of life.