解毒消痛贴外敷治疗湿热蕴结型急性痛风关节炎患者的临床效果观察

Clinical Effect of Jiedu Xiaotong Patch on Acute Gouty Arthritis with Damp-heat Accumulation

目的:观察对湿热蕴结型急性痛风关节炎(AGA)患者应用外敷解毒消痛贴治疗的临床效果。方法:选取2020年3月-2022年2月娄底市中心医院收治的80例湿热蕴结型AGA患者为研究对象,根据随机数字表法分为治疗组和对照组,各40例。两组均进行基础治疗,对照组在基础治疗基础上采用双氯芬酸二乙胺乳胶剂外涂进行治疗,治疗组在基础治疗基础上采用解毒消痛贴外敷治疗,比较两组疼痛情况、相关指标、中医证候积分、治疗效果。结果:治疗前,两组疼痛评分比较,差异无统计学意义(P>0.05);治疗后,治疗组疼痛评分低于对照组,差异有统计学意义(P<0.05)。治疗前,两组血尿酸、C反应蛋白、血沉水平比较,差异无统计学意义(P>0.05);治疗后,两组血尿酸水平比较,差异无统计学意义(P>0.05);治疗组血沉、C反应蛋白水平低于对照组,差异有统计学意义(P<0.05)。治疗前,两组中医证候积分比较,差异无统计学意义(P>0.05);治疗后,治疗组中医证候积分低于对照组,差异有统计学意义(P<0.05)。治疗组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论:解毒消痛贴外敷联合常规西药治疗对湿热蕴结型AGA患者的疗效显著,可迅速缓解患者的疼痛及相关症状,建议推广。

Objective:To observe the clinical effect of external application of Jiedu Xiaotong Patch on patients with acute gouty arthritis(AGA)due to damp-heat accumulation.Methods:Eighty patients with damp-heat-embedded AGA admitted to Loudi Central Hospital from March 2020 to February 2022 were selected as study subjects and divided into treatment group and control group according to the random number table method,40 cases each.Both groups received basic treatment.The control group received external application of diclofenac diethylamine emulsion on the basis of basic treatment.The treatment group received external application of Jiedu Xiaotong Patch on the basis of basic treatment.The two groups were compared in terms of pain,related indexes,TCM evidence points and treatment effects.Results:Before treatment,there was no statistically significant difference between the pain scores of the two groups(P>0.05);after treatment,the pain scores of the treatment group were lower than those of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the blood uric acid,C-reactive protein and sedimentation levels of the two groups(P>0.05);after treatment,there was no statistically significant difference between the blood uric acid levels of the two groups(P>0.05);the sedimentation and C-reactive protein levels of the treated group were lower than those of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the two groups(P>0.05);after treatment,the Chinese medicine evidence points of the treatment group were lower than those of the control group,and the difference was statistically significant(P<0.05).The total efficiency of treatment in the treatment group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The treatment of Jiedu Xiaotong Patch combined with conventional western medicine has a significant effect on patients with damp-heat accumulation type AGA,which can quickly relieve pain and related symptoms,so it is recommended to be popularized.