复方苓榆洗剂治疗婴儿湿热浸淫型湿疹临床研究

Clinical Study of Compound Lingyu Lotion(复方苓榆洗剂) in the Treatment of Infantile Eczema with Damp-Heat Syndrome

目的观察复方苓榆洗剂治疗婴儿湿热浸淫型湿疹的临床疗效。方法采用随机对照方法,将60例符合纳入标准的湿疹患儿分为治疗组和对照组,每组30例,治疗组采用复方苓榆洗剂外敷,对照组采用冰黄肤乐软膏外涂,通过SPSS 22.0统计分析,比较两组患儿红斑、丘疹/丘疱疹/水疱、糜烂、渗出/结痂/鳞屑、全身皮损面积、瘙痒症状程度积分。结果根据每组不同症状程度积分,计算两组相应频数,通过秩和检验比较两组差异,结果治疗组与对照组在患儿红斑、丘疹/丘疱疹/水疱、糜烂、渗出/结痂/鳞屑、瘙痒症状程度积分比较均有统计学意义(P<0.05),两组患儿全身皮损面积积分比较无统计学意义(P>0.05)。结论复方苓榆洗剂外用治疗婴儿湿热浸淫型湿疹,在红斑、丘疹/丘疱疹/水疱、糜烂、渗出/结痂/鳞屑、瘙痒症状改善方面优于冰黄肤乐软膏,在全身皮损面积改善方面,两组治疗方法疗效无明显差异。

Objective To observe the clinical efficacy of Compound Lingyu Lotion(复方苓榆洗剂)in the treatment of infantile eczema with damp-heat syndrome.Methods 60 children with eczema were randomly divided into treatment group and control group,with 30 cases in each group.The treatment group was treated with Compound Lingyu Lotion,and the control group was treated with Binghuang Fule Ointment(冰黄肤乐软膏).The scores of erythema,papule/herpes/blister,erosion,exudation/scab/scale,systemic lesion area and pruritus symptoms were compared between the two groups through SPSS 22.0 statistical analysis.Results According to the scores of symptom degrees of each group,the differences between the two groups were compared by statistical analysis.The scores of erythema,papule/herpes/blister,erosion,exudation/scab/scale and pruritus in the treatment group and the control group were statistically significant(P<0.05),but there was no significant difference between the two groups in skin lesion area(P>0.05).Conclusion Compound Lingyu Lotion is superior to Binghuang Fule Ointment in the improvement of erythema,papule/hillock herpes/blister,erosion,exudation/scab/scale and pruritus.There is no significant difference between the two groups in the improvement of systemic skin lesion area.