摘要
目的:分析老年冠心病患者介入术后再狭窄的危险因素。方法:选取2016年6月-2021年6月行经皮冠状动脉介入治疗(PCI)的老年冠心病患者128例为观察对象,术后12个月后进行冠状动脉造影复查判断支架内再狭窄(ISR)情况,比较出现ISR老年患者与未出现ISR老年患者基本资料,通过Logistic多因素回归分析PCI术后患者出现ISR的危险因素。结果:128例老年冠心病患者中出现ISR 45例,未出现ISR 83例;两组糖尿病病史、高血压病史、支架置入原因、冠状动脉病变支数、支架直径、支架位置、支架长度、不规律服药及低密度脂蛋白胆固醇(LDL-C)比较,差异有统计学意义(P<0.05);Logistic回归分析结果显示,糖尿病史、多支数病变、高血压史、不稳定型心绞痛、支架直径≥3 mm、支架置入在前降支、支架长度>20 mm、不按时服用抗血小板药物以及LDL-C≥1.8 mmol/L为老年冠心病患者行PCI术后出现ISR的危险因素(P<0.05)。结论:有糖尿病病史、高血压病史、不稳定型心绞痛、多支数病变、支架直径≥3 mm、支架置入在前降支、支架长度>20 mm、不规律服药及LDL-C≥11.8 mmol/L的老年冠心病患者在行PCI后更易引发ISR。
Objective:To analyze the risk factors of restenosis after intervention in elderly patients with coronary heart disease.Methods:128 elderly patients with coronary artery disease who underwent percutaneous coronary intervention(PCI)June 2016 to June 2021 were selected as observation subjects.Coronary angiography review was performed 12 months after the procedure to determine in-stent restenosis(ISR),and the basic data of elderly patients with ISR were compared with elderly patients without ISR.Risk factors for the development of ISR in patients after PCI were analyzed by logistic multifactorial regression.Results:45 cases of 128 elderly patients with coronary heart disease presented with ISR and 83 cases without ISR.The differences were statistically significant(P<0.05)when comparing the history of diabetes mellitus,history of hypertension,reason for stent placement,number of coronary artery lesion branches,stent diameter,stent location,stent length,irregular medication and lowdensity lipoprotein cholesterol(LDL-C)between the two groups.Logistic regression analysis showed that history of diabetes mellitus,multiple branch number lesions,history of hypertension,unstable angina,stent diameter≥3 mm,stent placement in the anterior descending branch,stent length>20 mm,irregular antiplatelet medication,and LDL-C≥1.8 mmol/L were risk factors for ISR after PCI in elderly patients with coronary artery disease(P<0.05).Conclusion:Elderly patients with coronary heart disease with a history of diabetes mellitus,hypertension,unstable angina,multi-branch lesions,stent diameter≥3 mm,stent placement in the anterior descending branch,stent length>20 mm,irregular medication and LDL-C≥11.8 mmol/L were more likely to develop ISR after PCI.
作者
赵华锋
王忠
邱际祥
Zhao Hua-feng;Wang Zhong;Qiu Ji-xiang(Department of Outpatient Clinic,Yantai Seventh Cadre's Sanitarium of Shandong Province Military Region,Yantai 264000,Shandong Province,China)
出处
《中外医药研究》
2022年第11期54-56,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
老年
冠心病
介入治疗
术后再狭窄
危险因素
Elderly
Coronary heart disease
Interventional therapy
Post-procedure restenosis
Risk factors