超声引导下射频消融与常规甲状腺手术对甲状腺良性肿瘤的临床效果对比分析

Clinical effect between ultrasound-guided radiofrequency ablation and conventional thyroid surgery on benign thyroid tumors

目的 分析超声引导下射频消融与常规甲状腺手术对甲状腺良性肿瘤的临床效果。方法选取2019年1月至12月商丘市第一人民医院收治的98例甲状腺良性肿瘤患者,根据不同治疗方式分为研究组(50例,超声引导下射频消融)与对照组(48例,常规甲状腺手术),对比2组临床疗效、手术指标(手术时间、术中出血量、住院时间)、甲状腺功能[血清三碘甲状腺原氨酸(T3)、四碘甲状腺原氨酸(T4)、游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)、促甲状腺素(TSH)]及并发症(声音嘶哑、颈部血肿、喉返神经损伤、颈部疼痛、甲状腺功能减退等)。结果 研究组临床总有效率为96%,对照组临床总有效率为94%,2组差异无统计学意义(P>0.05);研究组手术时间、术中出血量、住院时间比较研究组优于对照组(P<0.05);治疗后,2组T3、T4、FT3、FT4水平较术前降低,TSH较术前升高,且研究组T3、T4、FT3、FT4水平低于对照组,TSH高于对照组(P<0.05);研究组并发症发生率(8%)低于对照组(25%)(P<0.05)。结论 超声引导下射频消融治疗甲状腺良性肿瘤可促进患者甲状腺功能恢复,提升临床疗效,且术后并发症发生率低,美观度佳,值得临床推广。

Objective To compare the clinical effect between ultrasound-guided radiofrequency ablation and conventional thyroid surgery on benign thyroid tumors. Methods The 98 patients with benign thyroid tumors admitted to our hospital from January 2019 to December 2019 were selected and divided into study group(n=50,ultrasound-guided radiofrequency ablation)and control group(n=48,conventional thyroid surgery). The clinical efficacy, surgical indicators(operating time, intraoperative blood loss, length of hospitalization), thyroid function [serum triiodothyronine(T3),thyroxine(T4),and free triiodothyronine(FT3),free thyroxine(FT4),thyroid-stimulating hormone(TSH)]and complications(hoarse voice,neck hematoma,recurrent laryngeal nerve injury,neck pain,hypothyroidism,etc.)were compared between the two groups. Results The total effective rate of the study group was 96%,and that of the control group was 94%. There was no significant difference between the two groups(P>0.05). The operation time,intraoperative blood loss,and hospital stay in the study group were better than those in the control group(P<0.05). After treatment,the levels of T3,T4,FT3,and FT4 in the two groups were significantly lower than those before surgery,and TSH was significantly higher than that before surgery. The levels of T3,T4,FT3,and FT4 in the study group were lower than those in the control group,and TSH was higher than that in the control group(P<0.05). The incidence of complications in the study group(8%)was significantly lower than that in the control group(25%)(P<0.05). Conclusion Ultrasound-guided radiofrequency ablation in the treatment of benign thyroid tumors can promote the recovery of thyroid function in patients,improve clinical efficacy,and has a low incidence of postoperative complications and good aesthetics,which is worthy of clinical promotion.