一核多元团队干预模式结合有氧运动在免疫治疗肺癌患者中的应用

Application of one-core multi-group intervention model combined with aerobic exercise in immunotherapy of lung cancer patients

目的观察在免疫治疗肺癌(LCA)患者中实施一核多元团队干预模式结合有氧运动的临床效果。方法选取2019年12月—2021年12月于常州二院阳湖院区呼吸科接受免疫治疗98例肺癌患者为研究对象,按照组间基本特征具有可比性的原则分为对照组和观察组,各49例。对照组实施常规护理干预,观察组实施一核多元团队干预模式结合有氧运动。干预1个月后使用肺癌治疗功能评定量表(FACT-L)测评两组患者生活质量,并比较两组患者肺功能检测指标及6 min步行试验数值(6MWT)。结果干预前,两组患者生活质量、各项肺功能检测指标及6MWT比较,差异均无统计学意义(P>0.05);干预1个月后,观察组6MWT数值为123.05±8.98 m,对照组6MWT数值为117.65±7.66 m,差异有统计学意义(P<0.05)。观察组患者FACT-L量表各维度评分及肺功能检测指标均高于对照组,差异有统计学意义(P<0.05)。结论实施一核多元团队干预模式结合有氧运动能够最大程度上改善LCA患者的肺功能指标,从而提升生活质量。

Objective To observe the clinical effect of one-core multi-group intervention combined with aerobic exercise in immunotherapy patients with lung cancer(LCA).Methods 98 patients with lung cancer who received immunotherapy in the Respiratory Department of Yanghu Hospital of Changzhou Second Hospital from December 2019 to December 2021 were selected as the study objects.According to the principle of comparability of basic characteristics between groups,they were divided into control group and observation group,with 49 cases in each group.The control group received routine nursing intervention.The observation group received one-core multi-group intervention model combined with aerobic exercise.The Functional Assessemt of Cancer Therapy-L(FACT-L)was used 1 month after intervention.The quality of life of the two groups was assessed,and the lung function test indexes and the 6-Min Walking Test value(6MWT)were compared between the two groups.Results Before intervention,there were no significant differences in quality of life,lung function and 6MWT between 2groups(P>0.05).After 1 month of intervention,the 6MWT value in the observation group was 123.05±8.98 m,and that in the control group was 117.65±7.66 m,with statistical significance(P<0.05).FACT-L scale scores and lung function test indexes in observation group were higher than those in control group,and the difference was statistically significant(P<0.05).Conclusion The implementation of one-core multi-group intervention mode combined with aerobic exercise can maximize the improvement of lung function indexes in patients with LCA,thus improving quality of life.