复方巴戟天健骨颗粒的水提工艺优化研究

Optimization of Water Extraction Process of Compound BaJiTian JianGu Granules

目的优化复方巴戟天健骨颗粒的水提工艺。方法单因素考察溶媒使用量;以丹酚酸B等三种有效成份含量和干浸膏率的加权评分为综合指标,正交试验研究复方巴戟天健骨颗粒的水提工艺,并进行工艺验证。结果最佳工艺为药材浸泡60 min,10倍水提取3次,每次60 min。结论水提工艺合理、可靠、可行。

OBJECTIVE Optimization of Water Extraction Process of Fufangbajitian Jiangu Granules.METHODS With the comprehensive score of baicalin and dry extract rate as the evaluation index,the water estraction process of Compound BaJiTian JianGu Granules was optimi 2 ed by orthogonal test,and the reliability of the optimal process was verftied.RESULTS The best preparation process was as follow:The medicinal materials were soaked for 60 min,extracted 3 times with 10 times of extraction solvent,60 min each time.CONCLUSIONS The optimized centrifugal process of water extraction is reasonable,stable and reliable.