摘要
Over the past 2 years,many DNA motors have been synthesized and run in living cells,but there are still challenges in designing integrated DNA motors self-powered to enable autonomous intracellular walking without auxiliary additives.Herein,we report a smart strategy based on a DNA motor–MnO2 nanocomposite,which successfully meets these requirements of intracellular analysis and enables sensitive imaging of specific microRNAs(miRNAs)in living cells.
基金
support from the National Key R&D Program of China(grant no.2016YFA0201200)
the National Natural Science Foundation of China(grant no.21991080)
the Excellent Research Program of Nanjing University(ZYJH004).
