改良雷火灸联合温阳活血法治疗慢性萎缩性胃炎的疗效

Therapeutic Effect of Modified Thunder Fire Moxibustion Combined with Wenyang Huoxue Method on Chronic Atrophic Gastritis

目的:探讨改良雷火灸加温阳活血法治疗慢性萎缩性胃炎的临床效果。方法:选取2019年3月-2021年3月长垣中西医结合医院收治的慢性萎缩性胃炎患者80例为观察对象,根据随机数字表法分为对照组与观察组,各40例。对照组采用温阳活血法治疗,观察组在对照组基础上给予改良雷火灸治疗,比较两组患者临床效果、中医证候积分、病理积分、胃功能指标、幽门螺杆菌(Hp)根除率、疼痛程度。结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05);治疗后,两组患者胃痛胃胀、反酸嗳气、纳差、乏力中医证候积分均下降,观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者黏膜萎缩、肠上皮化生、异型增生病理积分均下降,观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者血清胃泌素-17、胃蛋白酶原水平均升高,观察组高于对照组,差异有统计学意义(P<0.05);观察组Hp清除率高于对照组,疼痛程度低于对照组,差异有统计学意义(P<0.05)。结论:改良雷火灸联合温阳活血法在慢性萎缩性胃炎治疗中,可加快疾病恢复速度,改善临床症状及胃功能指标,提高Hp清除率,降低疼痛程度,提高临床效果。

Objective:To investigate the clinical effect of modified thunder fire moxibustion combined with Wenyang Huoxue method in the treatment of chronic atrophic gastritis.Methods:Eighty patients with chronic atrophic gastritis admitted to Changyuan Hospital of Integrated Traditional Chinese and Western Medicine from March 2019 to March 2021 were selected as the observation objects.According to random number table method,they were divided into control group and observation group,40 cases in each group.The control group was treated with Wenyang Huoxue method,and the observation group was treated with modified thunder fire moxibustion on the basis of the control group.The clinical effect,TCM syndrome score,pathological score,gastric function index,eradication rate of Helicobacter pylori(Hp)and pain degree of the two groups were compared.Results:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of TCM syndrome of stomach pain and distension,acid belching,poor accommodation and fatigue in 2 groups all decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).After treatment,the pathological scores of mucosal atrophy,intestinal metaplasia and dysplasia were all decreased in 2 groups,and the observation group was lower than the control group,with statistical significance(P<0.05).After treatment,serum gastrin-17 and pepsin raw water in 2 groups were increased on average,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).The Hp clearance rate in the observation group was higher than that in the control group,but the pain degree was lower,and the difference was statistically significant(P<0.05).Conclusion:In the treatment of chronic atrophic gastritis,the modified thunder fire moxibustion combined with Wenyang Huoxue method can accelerate the recovery of the disease,improve clinical symptoms and gastric function indexes,increase the clearance rate of Hp,reduce the degree of pain,and improve the clinical effect.