Asymmetric Electrochemical Arylation in the Formal Synthesis of(+)-Amurensinine

Asymmetric electrochemical synthesis has emerged as an attractive and sustainable alternative for the distinctive activation of bond connections in the preparation of diverse enantiomerically enriched targets,including natural products and pharmaceutical agents.Herein,we describe the chiral Lewis acid-catalyzed enantioselective electrochemical anodic coupling reaction as a key step in the presented formal synthesis of isopavine alkaloids.