肺小结节患者的性格特征分析

Analysis of personality traits of patients with small pulmonary nodules

目的探索研究肺小结节患者是否具有某些特殊的行为特征,及其对结节性质的影响。方法本研究为横断面研究,采用非随机抽样的方法选取2021年1月至7月以肺结节为入院诊断的空军军医大学第二附属医院胸腔外科住院的患者316例,使用C型行为量表进行性格特征调查。比较病理结果为良性结节和恶性结节患者,以及恶性结节患者和C型行为量表常模不同性别的C型行为得分情况(焦虑、抑郁、愤怒、愤怒向内、愤怒向外、理智、控制、乐观和社会支持)。以腺癌的病理分级为因变量,以性别、年龄、C型行为得分为自变量,进行多因素有序logistic回归分析。结果调查的316例患者中,CT表现为实性结节的患者82例,混合磨玻璃结节170例,纯磨玻璃结节64例;病理结果为恶性患者行为量表中的愤怒、愤怒向内得分均低于良性组[(16.56±4.29)分比(18.65±5.15)分、(12.68±2.94)分比(13.80±2.64)分],差异均有统计学意义(t值分别为2.27、2.32,P值均<0.05)。男性肺癌患者中的抑郁、愤怒向外、乐观、社会支持得分与男性常模比较差异均有统计学意义(P值均<0.05);女性肺癌患者中抑郁、愤怒向外、乐观、社会支持得分与女性常模比较差异均有统计学意义(P值均<0.05)。性别、年龄、焦虑为肺腺癌病理分级的独立危险因素(P值均<0.05)。结论肺小结节患者具有C型行为特征,抑郁、愤怒向外、乐观、社会支持与结节性质相关;性别、年龄、焦虑是腺癌病理分级的独立危险因素。

Objective To explore the specific personality traits in patients with small pulmonary nodules,and their potential influence on the nature of the nodules.Methods This was a cross-sectional study.A non-random sampling method was used to select 316 patients with pulmonary nodules admitted to the Department of Thoracic Surgery,Second Affiliated Hospital of Air Force Medical University from January 2021 to July 2021.Their personality traits were assessed using the Type C Personality Scale.Specific personality traits in patients with benign and malignant pulmonary nodules were compared.Anxiety,depression,anger,exin-anger,exout-anger,rational,control,optimism,and social support scores in male and female patients with malignant pulmonary nodules were compared.Multivariable ordinal logistic regression was performed,in which tumor staging of lung adenocarcinoma was the dependent variable,and sex,age and Type C Personality scores were the independent variables.Results A total of 316 patients with pulmonary nodules were retrospectively analyzed,including 82 patients with solid nodules on CT scans,170 with mixed ground glass nodules and 64 with pure ground glass nodules.Anger scores([16.56±4.29]points vs[18.65±5.15],t=2.27)and exin-anger scores([12.68±2.94]points vs[13.80±2.64]points,t=2.32)in patients with malignant pulmonary nodules were significantly lower than those with benign ones(both P<0.05).There were significant differences in the depression,exout-anger,optimism and social support scores between male patients with malignant pulmonary nodules and healthy men(all P<0.05),and between female patients with malignant pulmonary nodules and healthy women(all P<0.05).Sex,age and anxiety were independent risk factors for the tumor staging of lung adenocarcinoma(all P<0.05).Conclusions Patients with small pulmonary nodules have type C personality traits.Depression,exout-anger,optimism and social support are significantly correlated with the nature of pulmonary nodules.Sex,age and anxiety are independent risk factors for the tumor staging of lung adenocarcinoma.