甲状旁腺切除术对继发性甲状旁腺功能亢进症患者生活质量影响的研究进展

Research progress on the effect of parathyroidectomy on the quality of life in patients with secondary hyperparathyroidism

继发性甲状旁腺功能亢进(secondary hyperparathyroidism,SHPT)是长期透析患者常见的严重并发症,患者常经历多种症状,生活质量低下。针对药物治疗不佳的严重SHPT患者,甲状旁腺切除术(parathyroidectomy,PTX)是效果确切的优选方案。而目前,PTX术后随访工作尚未得到足够重视,对患者的临床症状及生活质量评估尚不充分。鉴于此,我们系统梳理患者术后生活质量和相关症状的变化情况及其影响因素,旨在为今后开展此类患者的症状管理实践和研究提供参考。

Secondary hyperparathyroidism(SHPT)is a common and serious complication in long-term dialysis patients,who often experience multiple symptoms and a poor quality of life.Parathyroidectomy(PTX)is the best choice for severe SHPT patients with poor drug treatment.At present,the follow-up after PTX has not received sufficient attention,and the assessment of patients'clinical symptoms and quality of life is not yet adequate.In view of this,we systematically combed the changes and influencing factors of patients'quality of life and related symptoms after surgery,in order to provide reference for the practice and research of symptom management of such patients in the future.