摘要
Rationale:To report neurological paradox in a non-HIV patient with pulmonary tuberculosis.Patient concerns:A 26-year-old non-human immunodeficiency virus immunosuppressed female patient presented with diffused headache,diplopia,ascending paraparesis with loss of bowel and bladder control.Diagnosis:Disseminated neurological paradoxical reaction developed during tuberculosis treatment in a non-human immunodeficiency virus patient.Intervention:High-dose intravenous corticosteroid was added to the anti-tuberculous drugs,followed by tapered dose of oral prednisolone in 3 months.Outcome:A favorable neurological outcome was obtained 6 months later.Lessons:Neurological paradoxical reaction cannot be overlooked among the tuberculosis-treated cases who present with newly emerged neurological disorders.