广东省2018年≥18岁人群血脂异常流行特征及相关因素分析

Epidemiological characteristics and related factors of dyslipidemia in residents(≥18 years old)of Guangdong Province in 2018

目的了解2018年广东省居民不同特征人群血脂异常的流行水平及分布差异,探讨血脂异常的相关影响因素。方法数据来源于广东省2018年中国成人慢性病及危险因素监测,在广东省14个监测点中,采用多阶段分层整群随机抽样的方法抽取8497名调查对象开展现场调查。通过问卷调查、体格检查和实验室检测获取调查对象基本信息、身高、体重、腰围、血压、血脂和血糖水平。采用SPSS 22.0软件进行Rao-Scottχ~2检验和复杂抽样的二分类非条件logistic回归分析(Bootstrap法)。结果加权后,广东省成年居民血脂异常患病率为36.5%,高总胆固醇血症患病率为14.3%,高甘油三酯血症患病率为14.5%,高低密度脂蛋白胆固醇血症患病率为16.7%,低高密度脂蛋白胆固醇血症患病率为13.1%。多因素logistic回归分析结果显示,女性(OR=0.504)、农村居民(OR=0.803)与血脂异常患病低风险相关;而年龄≥60岁(OR=1.549),婚姻状况为已婚或同居(OR=1.604),丧偶、离婚或分居(OR=2.069),超重(OR=1.772),肥胖(OR=4.306)、中心性肥胖(OR=1.702)、高血压(OR=1.487)及糖尿病(OR=1.811)与血脂异常患病高风险相关,均有统计学意义(P<0.05,P<0.01)。结论2018年广东省成年居民血脂异常患病情况较为严峻。可通过采取生活方式干预等措施,控制广东省居民血脂异常危险因素的流行,从而降低血脂异常患病率。

Objective To understand the prevalence and distribution of dyslipidemia among residents with different characteristics of Guangdong Province in 2018,and explore the related influencing factors of dyslipidemia.Methods Data were from the surveillance of chronic diseases and risk factors in Guangdong Province of Chinese adults in 2018,the multi-stage stratified cluster random sampling method was used to select 8497 subjects from 14 monitoring points of Guangdong Province.The investigation was performed with questionnaire,physical measurement and laboratory test to collect the basic information,height,weight,waist circumference,blood pressure,blood lipid and blood glucose.Rao-Scottχ~2test and complex sampling binary unconditional logistic regression(Bootstrap method)were used to analyze the data,the used software was SPSS 22.0.Results After weighting,the morbidity of dyslipidemia,rates of high triglyceride,high total cholesterol,high low density lipoprotein cholesterol and low high density lipoprotein cholesterol were 36.5%,14.3%,14.5%,16.7%and 13.1%,respectively.The multivariate logistic regression showed that female(OR=0.504)and rural residents(OR=0.803)were related to low risk of dyslipidemia;but age≥60 years old(OR=1.549),married or cohabit(OR=1.604),widow,divorce or separation(OR=2.069),overweight(OR=1.772),obesity(OR=4.306),central obesity(OR=1.702),hypertension(OR=1.487)and diabetes(OR=1.811)were related to the high risk of dyslipidemia(P<0.05 or P<0.01).Conclusion The morbidity of dyslipidemia in adult residents of Guangdong Province in 2018 is higher.Lifestyle intervention measures for Guangdong residents should be taken to control the prevalence of risk factors for dyslipidemia and to reduce the morbidity of dyslipidemia.