活血止痛膏外敷辅助治疗单纯性肋骨骨折的临床效果

Clinical effect of adjuvant therapy of topical application with Huoxue Zhitong Ointment in the treatment of simple rib fracture

目的探究活血止痛膏外敷辅助治疗单纯性肋骨骨折的临床效果。方法选取江苏省泰州市中西医结合医院2017年9月至2021年12月收治的112例单纯性肋骨骨折患者作为研究对象,采用随机数字表法将其分为研究组和对照组,均56例。对照组予以基础治疗及弹力肋骨带外固定,研究组在对照组基础上联合活血止痛膏外敷,1个月后评估两组疗效。比较两组治疗前及治疗1个月后的中医证候积分、血清炎症因子水平、疼痛程度及睡眠质量,并观察治疗期间并发症及药物不良反应发生情况。结果研究组临床疗效优于对照组,骨骼愈合时间短于对照组(P<0.05)。治疗1个月后,两组主证积分、次证积分、中性粒细胞弹性蛋白酶、白细胞介素-10、视觉模拟评分法评分、匹斯堡睡眠质量指数均低于治疗前,且研究组低于对照组(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。两组治疗期间均未出现明显药物不良反应。结论活血止痛膏外敷辅助保守治疗单纯性肋骨骨折有助于降低患者机体的炎症反应,促进患者恢复,临床效果较好。

Objective To explore the clinical effect of adjuvant therapy of topical application with Huoxue Zhitong Ointment in the treatment of simple rib fracture.Methods A total of 112 patients with simple rib fracture admitted to Taizhou Hospital of Integrated Traditional Chinese and Western Medicine in Jiangsu Province from September 2017 to December 2021 were selected as the research objects.They were divided into study group and control group by random number table method,with56 cases in both groups.The control group was given basic treatment and elastic rib external fixation,and the study group was combined with adjuvant therapy of topical application with Huoxue Zhitong Ointment on the basis of the control group.The efficacy of both groups was evaluated after one month of treatment.Traditional Chinese medicine syndrome scores,serum inflammatory factor levels,pain degree,and sleep quality of the two groups were compared before and after treatment for one month,and the complications and adverse drug reactions during treatment was observed.Results The clinical efficacy of the study group was better than that of the control group,and the bone healing time was shorter than that of the control group(P<0.05).After one month of treatment,the main syndrome score,secondary syndrome score,neutrophil elastase,interleukin-10,visual analog scale score,and Pittsburgh sleep quality index of both groups were lower than those before treatment,and those of the study group were lower than the control group(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).There was no obvious adverse drug reaction in the two groups during treatment.Conclusion Adjuvant therapy of topical application with Huoxue Zhitong Ointment combined with conservative treatment for simple rib fracture is more helpful to reduce the inflammatory reaction and promote the recovery of patients,the clinical effect is superior.