卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的疗效研究

Clinical effect of carprost amine triol injection on postpartum hemorrhage caused by uterine fatigue

目的探究卡前列素氨丁三醇注射液在宫缩乏力性产后出血患者治疗中的临床效果。方法选取60例宫缩乏力性产后出血患者,基于系统随机分组原则分组为常规组与试验组,每组30例。常规组接受催产素治疗,试验组接受卡前列素氨丁三醇注射液治疗。比较两组治疗效果、阴道出血时间、住院时间、血红蛋白水平、不良反应,并评估生活质量。结果试验组阴道出血时间(31.55±3.98)h、住院时间(6.80±1.04)d、血红蛋白水平(92.36±8.59)g/L,常规组分别为(47.50±4.30)h.(9.27±2.71)d.(79.64±8.33)g/L,比较差异有统计学意义(P<0.05)。试验组生活质量评分高于常规组,差异有统计学意义(P<0.05)。试验组治疗总有效率高于常规组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血患者的效果确切,止血效果显著,提高血红蛋白水平,减短住院时间,提高患者生活质量,安全有效,可推广应用。

Objective To explore the clinical effect of carprost amine triol injection in the treatment of postpartum hemorrhage caused by uterine fatigue.Methods 60 patients with postpartum hemorrhage due to uterine fatigue were divided into conventional group and experimental group based on systematic randomization principle,with 30 cases in each group.The conventional group received oxytocin treatment,and the experimental group received carprost amine injection.Treatment effect,duration of vaginal bleeding,length of hospital stay,hemoglobin level,adverse reactions,and quality of life were compared between the two groups.Results The duration of vaginal bleeding(31.55±3.98)h,length of hospital stay(6.80±1.04)d and hemoglobin level(92.36±8.59)g/L in experimental group were(47.50±4.30)h,(9.27±2.71)d and(79.64±8.33)g/L in conventional group,respectively.The difference was statistically significant(P<0.05).The life quality score of experimental group was higher than that of conventional group,and the difference was statistically significant(P<0.05).The total effective rate of experimental group was higher than that of conventional group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical application of carprost amine triol injection in the treatment of postpartum hemorrhage patients with uterine fatigue has definite effect,remarkable hemostatic effect,improve the body hemoglobin,reduce the length of hospital stay,improve the quality of life of patients,safe and effective,can be popularized.