支原体肺炎患儿CT影像学特征及与肺通气功能的相关性

Correlation between CT imaging features and pulmonary ventilation function in children with Mycoplasma pneumoniae pneumonia

目的观察支原体肺炎(MPP)患儿CT影像学特征与肺通气功能情况,并分析二者之间的相关性。方法回顾性分析泾县医院2019年7月至2021年7月收治的100例MPP患儿的临床资料,根据患儿有无喘息症状/体征将其分为喘息组(n=52)与非喘息组(n=48),对比两组患儿CT评分及肺通气功能,分析MPP患儿CT影像学特征及肺通气功能与CT评分之间的相关性。结果入组的100例MPP患儿中,经CT检查,病灶分布以小叶中心分布为主(90.00%),树芽征及淋巴管占比较少;病变形态团片状为49.00%,病变密度磨玻璃样改变为46.00%,未出现空洞现象。非喘息患儿CT评分低于喘息患儿,差异有统计学意义[(3.82±0.52)分vs(9.52±1.25)分,t=30.175,P<0.01]。与喘息组相比,非喘息组MPP患儿用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、FEV1/FVC均较高,组间比较差异均有统计学意义(P<0.01)。双变量Pearson直线相关性分析显示,MPP患儿CT评分与肺通气功能FVC呈负相关(r=-0.286,P<0.01),与FEV1呈负相关(r=-0.279,P<0.01),与FEV1/FVC呈负相关(r=-0.312,P<0.01)。结论MPP患儿CT评分与肺通气功能密切相关。临床可对患儿及时开展CT检查,并据此评估患儿肺通气功能情况。

Objective To observe the CT imaging features and pulmonary ventilation function in children with Mycoplasma pneumoniae pneumonia(MPP),and to analyze the correlation between them.Methods The clinical data of 100 children with MPP admitted to Jingxian Hospital from July 2019 to July 2021 were analyzed retrospectively.The children were divided into wheezing group(n=52)and non-wheezing group(n=48)according to wheezing symptoms/signs.The CT scores and pulmonary ventilation function of the two groups were compared,and the correlation between the CT imaging characteristics and the pulmonary ventilation function and CT scores of MPP children was analyzed.Results Among the 100 MPP children,CT examination showed that the distribution of lesions was mainly lobular-centered in 90 cases(90.00%),with few tree bud sign and lymphatic vessels,49.00%of the lesions morphology were lumpy and flaky,46.00%of lesion density was ground glass,and no cavity was found.The CT score of non-wheezing children was lower than that of wheezing children(3.82±0.52 vs 9.52±1.25,t=30.175,P<0.01).Compared with the wheezing group,the indexes forced vital capacity(FVC),forced expiratory volume in First second(FEV1),FEV1/FVC of MPP children in the non-wheezing group were higher(P<0.01).The bivariate Pearson linear correlation analysis showed that the CT score of MPP children was negatively correlated with FVC of pulmonary ventilation function(r=-0.286,P<0.01),FEV1of pulmonary ventilation function(r=-0.279,P<0.01),and FEV1/FVC of pulmonary ventilation function(r=-0.312,P<0.01).Conclusion The CT scores are closely related to pulmonary ventilation function in children with MPP.CT examination can be carried out in time to evaluate the pulmonary ventilation function of children with MPP.