基于“少阳主枢”理论探讨COPD合并焦虑抑郁的中医病机

Discussion on TCM Pathogenesis of COPD Complicated with Anxiety and Depression Based on “Action of Yang Collateral from Shaoyang Meridian”

慢阻肺是临床常见的一种慢性全身炎症性疾病,发病率及病死率逐年增高。由于慢阻肺疾病病程迁延,反复发生肺部感染,长期服药,导致肺功能下降,常合并多种并发症,加之家庭经济负担过重等多重因素,患者极易出现焦虑、抑郁等不良负性情绪,对疾病治疗及预后产生严重影响。目前,对慢阻肺合并焦虑抑郁的中西医研究比较缺乏,其相关机制并不完全清楚,试从“少阳枢机”理论探讨慢阻肺合并焦虑、抑郁状态的发病机制,以期为该病临床治疗提供新思路。

Chronic obstructive pulmonary disease(COPD) is a common chronic systemic inflammatory disease with increasing morbidity and mortality year by year. Due to the prolonged course of chronic obstructive pulmonary disease, repeated pulmonary infections, and long-term medication use, resulting in decreased lung function, multiple complications are often combined, and multiple factors such as excessive family economic burden, patients are prone to anxiety, depression and other adverse negative effects. Emotions have a serious impact on disease treatment and prognosis. At present, there is a lack of Chinese and Western medicine research on COPD combined with anxiety and depression, and the related mechanism is not completely clear. Try to explore the pathogenesis of COPD combined with anxiety and depression from the “Shaoyang Shuji” theory, in order to provide clinical evidence for the disease. Treatment offers new ideas.