摘要
On 7 January 2022,a 57-year-old man with terminal heart disease became the first living human to receive a genetically modified pig organ—a heart—transplanted into his chest during a 8 h surgery at the University of Maryland Medical Center in Baltimore,MD,USA(Fig.1)[1].The pig heart,provided by the biotechnology company Revivicor(Blacksburg,VA,USA),had ten gene modifications intended to boost the chances of a successful pig-to-human transplant.