低共熔溶剂提取海洋活性物质研究进展

Advances in extracting marine active substances using deep eutectic solvents

海洋活性物质是指对生命活动有影响的海洋生物组分或代谢产物,在医药、化妆品、保健食品等领域具有广泛的应用。低共熔溶剂(deepeutecticsolvent,DES)是基于离子液体所发展而来的一种新型绿色溶剂,它具备可设计、可回收、生物相容性高、合成简易及成本低廉等多重优势,在天然活性物质的提取中具有巨大的应用前景,引起了国内外研究学者的广泛关注。本文综述了DES在海洋活性物质(包括海洋多糖、蛋白质、DNA、生物柴油、酚类和萜烯类化合物等)提取中的应用,以期为海洋活性物质的绿色提取和应用提供新的策略。

Marine active substances refer to the biological components or metabolites present in marine organisms,which affect life activities and are widely used in medicine, cosmetics, health food, and other fields. As novel green solvents derived from ionic liquid, deep eutectic solvents(DESs) have many advantages, including designability,recyclability, high biocompatibility, easy synthesis, and low cost. Therefore, DESs have attracted the attention of researchers and have application prospects for extracting naturally active substances. Here, a comprehensive review on extracting marine active substances with DESs, including marine polysaccharides, proteins, DNA, biodiesel,phenolic compounds, and terpenes, is discussed to provide a new strategy for green extraction and applications for marine active substances.