精神疾病合并糖尿病患者血脂检验结果的分析

Analysis of the results of blood lipid test in patients with mental illness and diabetes mellitus

目的 研究分析精神疾病合并糖尿病患者的血脂检验结果。方法 回顾性选取精神疾病合并糖尿病患者35例作为实验组,另选同期健康体检者35例作为对照组。实验组患者给予对症治疗,两组均行血脂相关指标检验。对比实验组治疗前和对照组血脂指标[甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]、实验组患者治疗前后血脂指标。结果实验组患者治疗前的TG(2.12±0.58)mmol/L、TC(4.42±1.68)mmol/L、LDL-C(3.84±1.01)mmol/L均高于对照组的(1.62±0.38)、(3.22±1.28)、(2.34±0.15)mmol/L,差异有统计学意义(P<0.05);实验组治疗前和对照组的HDL-C水平对比,差异无统计学意义(P>0.05)。实验组患者治疗后的TG、TC、LDL-C水平分别为(1.72±0.18)、(3.45±0.23)、(2.45±0.56)mmol/L,均明显低于治疗前的(2.12±0.58)、(4.42±1.68)、(3.84±1.01)mmol/L,差异有统计学意义(P<0.05);实验组患者治疗前后的HDL-C水平对比,差异无统计学意义(P>0.05)。结论 精神疾病合并糖尿病患者血脂代谢会发生紊乱,通过血脂检验可有效判断病情的发展程度,临床应用价值较高。

Objective To study and analyze the results of blood lipid test in patients with mental illness and diabetes mellitus. Methods 35 patients with mental illness and diabetes mellitus were retrospectively selected as the experimental group, and another 35 patients with physical examination during the same period were selected as the control group. Patients in the experimental group were treated with symptomatic treatment,and patients in both groups were tested for blood lipid related indicators. Comparison was made on blood lipid indexes [triglyceride(TG), total cholesterol(TC), low density lipoprotein cholesterol(LDL-C), high density lipoprotein cholesterol(HDL-C)] between the experimental group before treatment and the control group, as well as the blood lipid indexes of the experimental group before and after treatment. Results The experimental group had TG of(2.12±0.58) mmol/L, TC of(4.42±1.68) mmol/L, LDL-C of(3.84±1.01) mmol/L before treatment,which were higher than(1.62±0.38),(3.22±1.28),(2.34±0.15) mmol/L in the control group, and the differences were statistically significant(P<0.05). There was no statistically significant difference in HDL-C levels between the experimental group before treatment and the control group(P>0.05). The levels of TG, TC and LDL-C in the experimental group after treatment were(1.72±0.18),(3.45±0.23) and(2.45±0.56) mmol/L, which were significantly lower than(2.12±0.58),(4.42±1.68) and(3.84±1.01) mmol/L before treatment, and the differences were statistically significant(P<0.05). There was no statistically significant difference in HDL-C levels in the experimental group before and after treatment(P>0.05). Conclusion Lipid metabolism in patients with mental illness and diabetes mellitus can be disturbed. By testing blood lipids, the degree of development of the disease can be judged effectively, and the clinical application value is high.