超声多模态成像技术鉴别诊断甲状腺良恶性结节的应用价值

Application value of ultrasonic multimodal imaging technology in differential diagnosis of benign and malignant thyroid nodules

目的探讨超声多模态成像技术鉴别诊断甲状腺良恶性结节的应用价值。方法选取2021年1月-2022年5月佛山海关口岸门诊部收集的甲状腺结节出入境人员35例为研究对象,均进行常规超声、彩色多普勒超声、超声弹性成像等超声多模态成像技术检查,最终以病理学检查为金标准。对比分析常规超声、彩色多普勒超声、超声弹性成像技术单项及联合对甲状腺结节良恶性的检出率,明确甲状腺结节在各项成像技术下的良恶性特征,对比分析各项技术单项及联合对甲状腺结节恶性的诊断价值。结果在35例甲状腺结节患者中,共有42个结节,常规超声对甲状腺良恶性结节检出率为57.14%,彩色多普勒超声对甲状腺良恶性结节检出率为61.90%,超声弹性成像对甲状腺良恶性结节检出率为76.19%,超声多模态成像对甲状腺良恶性结节检出率为95.24%;常规超声和彩色多普勒超声的成像特征中,病灶大小、数目、周围声晕鉴别甲状腺良恶性结节差异无统计学意义(P>0.05),病灶形态、边界、内部回声、后方回声衰减、钙化、纵横比、周围血流鉴别甲状腺良恶性结节差异有统计学意义(P<0.05);甲状腺良恶性结节的超声弹性成像均质度差异无统计学意义(P>0.05),弹性成像分级差异有统计学意义(P<0.05);超声多模态成像技术诊断甲状腺恶性结节的灵敏度、特异度、准确度最高,分别为96.00%、94.12%、95.24%。结论甲状腺良恶性结节运用超声多模态成像技术鉴别诊断的应用价值较高,准确度高。

Objective To explore the application value of ultrasonic multimodal imaging technology in differential diagnosis of benign and malignant thyroid nodules.Methods Selected 35 cases of thyroid nodule entry and exit personnel collected from the outpatient department of Foshan Customs Port from January 2021 to May 2022as the research object,All patients were examined by conventional ultrasound,color Doppler ultrasound,ultrasound elastography and other ultrasound multimodal imaging techniques,and ultimately pathological examination was the gold standard.Comparative analysis of the detection rates of conventional ultrasound,color Doppler ultrasound,and ultrasound elastography alone and in combination for benign and malignant thyroid nodules,To clarify the benign and malignant characteristics of thyroid nodules under various imaging techniques,Comparative analysis of the diagnostic value of each technique alone and combination in malignant thyroid nodules and drawing of ROC curve.Results Among the 35 patients with thyroid nodules,a total of 42 nodules,the detection rate of benign and malignant thyroid nodules by conventional ultrasound was 57.14%,the detection rate of benign and malignant thyroid nodules by color Doppler ultrasound was 61.90%,and the detection rate of benign and malignant thyroid nodules by ultrasound elastography was 76.19%,and the detection rate of benign and malignant thyroid nodules by ultrasound multimodal imaging was 95.24%;In the imaging characteristics of conventional ultrasound and color Doppler ultrasound,there was no significant difference in the size,number of lesions,and surrounding halo in distinguishing benign and malignant thyroid nodules(P>0.05),There were significant differences in lesion shape,boundary,internal echo,posterior echo attenuation,calcification,aspect ratio,and peripheral blood flow to differentiate benign and malignant thyroid nodules(P<0.05);There was no significant difference in ultrasound elastography homogeneity between benign and malignant thyroid nodules(P>0.05),but there was a statistically significant difference in elastography grade(P<0.05);Ultrasound multimodal imaging technology has the highest sensitivity,specificity,and accuracy in diagnosing malignant thyroid nodules,which are 96.00%,94.12%,and95.24%,respectively.Conclusion Ultrasound multimodal imaging technology has high application value and high accuracy in the differential diagnosis of benign and malignant thyroid nodules.