儿童先天性腹股沟斜疝发病危险因素分析

Analysis of riskfactors ofcongenital obliqueinguinal hernia inchildren

目的探讨儿童先天性腹股沟斜疝发病危险因素。方法选择2018年2月至2020年6月352例先天性腹股沟斜疝患者为斜疝组,以性别、年龄(±0.5)岁进行1:1配比选择同期住院的无腹外疝、先天性畸形及恶性肿瘤的352例住院患儿为对照组。收集可能影响儿童先天性腹股沟斜疝发病危险因素,单因素分析行X检验或t检验,多因素分析采用Logistic回归。P<0.05为差异有统计学意义。结果单因素基础上多因素Logistic回归分析结果显示:出生体质量<2.5kg(0R=1.571,95%CI=1.111-2.223)、有腹股沟家族史(0R=1.589,95%CI=1.112-2.270)、母亲妊娠期有贫血史(0R=1.508,95%CI=1.054-2.159)、母亲围孕期饮茶≥1次/周(0R=1.531,95%CI=1.099-2.132)及有母亲主/被动吸烟史(0R=1.536,95%CI=1.136-2.077)为儿童先天性腹股沟斜疝发病的危险因素(P<0.05)。结论儿童先天性腹股沟斜疝的发病与患儿出生体质量、腹股沟疝家族史等因素有关,临床上可通过对上述因素进行干预以降低先天性腹股沟斜疝的发生率。

Objective To investigate the risk factors of congenital oblique inguinal hernia in children.Methods352 cases of congenital inguinal hernia patients from February 2018 to June 2020 were selected as the inclined hernia group,and 352 cases of hospitalized children without external abdominal hernia,congenital malformation or malignant tumor were selected as the control group by 1:1 ratio of gender and age(±O.5)years.The risk factors that may affect the incidence of congenital oblique inguinal hernia in children were collected.Univariate analysis was performed by Chi-square test or t test,and multivariate analysis was performed by Logistic regression.P<0.05 was considered statistically significant.ResultsThe results of multivariate Logistic regression analysis on the basis of single factor showed that:Birth weight<2.5 kg(OR=1.571,95%Cl=1.111-2.223),family history of groin(0R=1.589,95%CI=1.112-2.270),maternal history of anemia during pregnancy(0R=1.508,95%CI=1.054-2.159),maternal tea drinking≥1 times/week during perinational pregnancy(0R=1.531,95%CI=1.099-2.132)and maternal history of active/passive smoking(OR=1.536,95%CI=1.136-2.077)was a risk factor for congenital oblique inguinal hernia in children(P<0.05).ConclusionThe incidence of congenital oblique inguinal hernia in children is related to birth weight,family history of inguinal hernia and other factors.Clinical intervention of these factors can reduce the incidence of congenital oblique inguinal hernia.