纳米靶向载药系统在前列腺癌治疗领域中的研究进展

Nanocarriers-mediated drug delivery systems for prostate cancer treatment: an overview and perspectives

我国前列腺癌发病率逐年升高,严重威胁男性生命健康。手术治疗、放疗、内分泌治疗与化疗是针对前列腺癌常见治疗手段,这些治疗手段有效改善了前列腺癌患者整体预后情况,但是仍然存在肿瘤复发、肿瘤耐药、严重并发症等诸多问题。随着纳米技术的发展,纳米靶向载药系统的应用有望提升前列腺癌治疗效果并减轻治疗不良反应,本文概述了纳米靶向载药系统在前列腺癌治疗领域中的最新研究进展,并展望未来研究方向。

Prostate cancer(PCa)is a major cause of morbidity and mortality in China.Nowadays,great progress has been achieved in surgical and pharmaceutical treatment of PCa,but there are still some obstacles to be solved.With the development of nanotechnology,the emergence of nanocarriers-mediated drug delivery systems(NDDS)has brought new strategies to the treatment of PCa.This review focused on and summarized the latest advancements of NDDS in PCa treatment.