基于络病理论探析大肠癌肝转移的病机演变

Pathogenesis of Liver Metastasis from Colorectal Cancer:Based on Collateral Disease Theory

络病理论是中医药认识疾病的重要参考。大肠癌肝转移是由多因素共同参与,分阶段分步骤发展而成的转移性恶性肿瘤,严重影响大肠癌患者的预后。大肠癌肝转移的病机演变与多种络脉病变机理相通。文中基于络病理论,结合现代研究机制,从气络和血络层面分析了大肠癌自发生至肝转移过程的病机演变,为中医药认识肝转移阶段和辨证治疗提供新的思路。

Collateral disease theory is important for the understanding of diseases in traditional Chinese medicine.Caused by multiple factors,liver metastasis from colorectal cancer develops step by step,posing a threat to the prognosis of patients with colorectal cancer.The pathogenesis of liver metastasis from colorectal cancer is consistent with that of multiple collateral diseases.According to modern research,this paper analyzes the variation of pathogenesis from the occurrence of colorectal cancer to liver metastasis from colorectal cancer based on the qi collateral theory and blood collateral theory,the two branches of collateral disease theory,which is expected to provide a new mindset for the understanding of liver metastasis from colorectal cancer and the syndrome differentiation and treatment in traditional Chinese medicine.