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R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response

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摘要 R-loops are RNA-DNA-hybrid-containing nucleic acids with important cellular roles.Deregulation of R-loop dynamics can lead to DNA damage and genome instability1,which has been linked to the action of endonucleases such as XPG2-4.However,the mechanisms and cellular consequences of such processing have remained unclear.
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出处 《四川生理科学杂志》 2022年第12期2163-2163,共1页 Sichuan Journal of Physiological Sciences
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