中药直肠滴入辅助治疗气滞血瘀型慢性骨盆疼痛综合征的临床观察

Clinical observation on rectal drip of traditional Chinese medicine in the treatment of chronic pelvic pain syndromes of Qi stagnation and blood stasis

目的 观察中药直肠滴入辅助治疗气滞血瘀型慢性骨盆疼痛综合征(CPPS)的临床疗效。方法 选取2021年7月至2022年1月湖南中医药大学第一附属医院诊治的80例气滞血瘀型CPPS患者作为研究对象。随机分为治疗组和对照组,每组40例,两组在常规服用坦索罗辛和三橘荔核汤治疗的基础上,分别应用中药直肠滴入与蒸馏水直肠滴入治疗。观察两组治疗前后慢性前列腺炎症状指数(NIH-CPSI)、中医辨证评分、前列腺按摩液(EPS)多媒体显微诊断白细胞计数(WBC)和卵磷脂小体计数(LP)及临床疗效。结果 治疗后,两组NIH-CPSI、中医辨证评分、WBC均有所降低,且治疗组的降低程度较对照组更为明显,差异具有统计学意义(P<0.05)。治疗组总有效率优于对照组,差异具有统计学意义(P<0.05)。结论 在口服中药西药常规治疗的基础上,加用中药直肠滴入治疗,能够更有效地降低气滞血瘀型CPPS患者的NIH-CPSI、中医辨证评分和EPS多媒体显微诊断WBC,改善临床症状,提高生活质量。

Objective To observe the clinical effect of rectal drip of Chinese herbal medicine on chronic pelvic pain syndrome(CPPS) of Qi stagnation and blood stasis type. Methods 80 patients with CPPS of Qi stagnation and blood stasis type diagnosed and treated in the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine from July 2021 to January 2022 were selected as the research objects. They were randomly divided into the treatment group and the control group, with 40 cases in each group. On the basis of routine treatment with tamsulosin and Sanju Lihe decoction, the two groups were respectively treated with rectal drip of traditional Chinese medicine and rectal drip of distilled water. The symptom index of chronic prostatitis(NIH-CPSI), traditional Chinese medicine syndrome differentiation score, white blood cell count(WBC) and lecithin corpuscle count(LP) of multimedia microscopic diagnosis of prostate massage fluid(EPS) and clinical efficacy were observed before and after treatment. Results After treatment, NIH-CPSI, traditional Chinese medicine syndrome differentiation score and WBC in the two groups were decreased, and the reduction in the treatment group was more significant than that in the control group, with a statistically significant difference(P<0.05). The total effective rate of the treatment group was better than that of the control group, with a statistically significant difference(P<0.05). Conclusions On the basis of routine treatment of oral traditional Chinese medicine and western medicine, the addition of rectal drip of traditional Chinese medicine can more effectively reduce NIH-CPSI, traditional Chinese medicine syndrome differentiation score and EPS multimedia microscopic diagnosis WBC of CPPS patients with Qi stagnation and blood stasis, improve clinical symptoms and improve quality of life.