以胃息肉为表现的神经内分泌肿瘤的临床特点分析

Clinical characteristics of neuroendocrine tumors with gastric polyps

目的:分析22例以胃单发或者多发息肉为表现的胃神经内分泌肿瘤的临床特征,避免临床对胃神经内分泌肿瘤的漏诊。方法:搜集2016年9月至2021年3月在南充市中心医院胃镜室行胃镜检查并经最终病理结果证实为胃神经内分泌肿瘤患者的临床资料,分析其性别、年龄、肿瘤发生部位、息肉多发单发情况、肿瘤浸润深度、肿瘤分级,于白光胃镜下、窄带成像放大胃镜下(ME+NBI)观察病变的临床特点。结果:经病理证实的22例胃神经内分泌肿瘤患者的具体情况如下:性别:女性16例,男性6例;年龄:位于45~70岁之间,中位年龄50.05岁;病灶部位:贲门2例、胃底5例、胃体15例;以胃息肉多发为表现者15例,以胃息肉单发为表现者7例;病灶大小在0.5~0.8 cm之间,肿瘤浸润深度以黏膜层为主,分级为G1级。在白光胃镜下大多表现为顶部糜烂、粗糙;NBI+ME表现为微结构增粗、形态不规则,微血管多变粗、形态不规则。结论:在临床胃镜检查过程中,需要警惕以胃息肉为表现的肿瘤可能是胃神经内分泌肿瘤。

Objective:To analyze the clinical features of 22 cases of gastric neuroendocrine tumors with single or multiple gastric polyps,so as to avoid the missed diagnosis of gastric neuroendocrine tumors.Methods:Clinical data of patients who underwent gastroscopy in the gastroscopy room of Nanchong Central Hospital from September 2016 to March 2021 and were confirmed as gastric neuroendocrine tumor by final pathological results were collected,and their gender,age,location of tumor occurrence,multiple and single polyps,depth of tumor invasion,and tumor grade were analyzed.The clinical features of the lesions were observed under white light gastroscope and narrow band imaging magnification gastroscope(ME+NBI).Results:The specific conditions of the 22 patients with gastric neuroendocrine tumor confirmed by pathology were as follows:gender:16 cases were female,6 cases were male;Age:between 45 and 70 years old,median age:50.05 years old;Lesion sites:cardia in 2 cases,fundus in 5 cases,body of the stomach in 15 cases;There were 15 patients with multiple gastric polyps and 7 patients with single gastric polyps.The size of the lesion was between 0.5 and 0.8 cm,and the depth of tumor invasion was mainly mucous layer with G1 grade.Under the white light gastroscope,most of them showed erosion and rough at the top.NBI+ME showed thickened microstructure and irregular morphology,and varied thick and irregular morphology of microvessels.Conclusion:In the course of clinical gastroscopy,it is necessary to be vigilant that the tumors manifested as gastric polyps may be gastric neuroendocrine tumors.