外阴上皮内瘤变的研究进展

Research progress of vulvar intraepithelial neoplasia

外阴上皮内瘤变(VIN)作为外阴鳞状细胞癌(VSCC)的前体病变,其恶变程度较高、发展迅速且复发风险高。VIN诱发因素非单一性,患者主要以外阴瘙痒、不适等临床症状而被发现。目前治疗方法并没有统一标准,预后也不能达到完全治愈,以上可能与个体差异和需求有关。因此,早发现、早治疗,坚持定期随访和复查是防治的关键。本文对近年VIN的研究进展作一简要综述。

As a precursor les ion of vulvar s quamous cell carcinoma(VSCC),vulvar intraepithelial neoplasia(VIN)has a high degree of malignancy,rapid development and high risk of recurrence.The inducing factors of VIN is not single,and the patients are mainly found with clinical symptoms such as vulvar pruritus and discomfort.At present,there is no unified standard for treatment,and the prognosis can not achieve complete cure,which may be related to individual differences and needs.Therefore,early detection and treatment,regular follow-up and review are the key to prevention and treatment.This article briefly reviews the research progre ss of VIN in recent years.