自体脂肪移植在口周及下面部年轻化中的应用

Autologous fat grafting for perioral and lower face rejuvenation

目的综述自体脂肪移植在口周及下面部年轻化中的应用研究进展。方法广泛查阅国内外相关研究文献,结合团队临床应用经验,就口周及下面部脂肪室及血供等解剖特点、老化特征以及自体脂肪移植在该区域年轻化治疗中的应用进展、相关并发症等进行广泛总结。结果口周及下面部区域包含唇部、颏部等美学标志,具有下颌脂肪室、颏部脂肪室等自体脂肪填充相关解剖结构,且面动脉途经该区域并发出重要分支。口周及下面部老化包括鼻唇沟加深、唇部老化、口周皱纹、“木偶纹”等。自体脂肪移植可恢复面部脂肪室容量,纠正老化畸形,改善肤质,促进口周及下面部年轻化,但存在神经血管损伤、面部美学问题等相关并发症。结论自体脂肪移植可用于口周及下面部年轻化治疗,能有效改善相关老化特征。国人面部美学特征相关研究、自体脂肪移植联合手术等综合治疗面部衰老,以及脂肪衍生物在口周及下面部年轻化中的应用均不断发展,但仍存在面部脂肪移植重吸收率高、远期效果不确定的问题,未来需探索提升移植脂肪存活率相关解决方案。

Objective To review the research progress of the application of autologous fat grafting in perioral and lower face rejuvenation.Methods By extensively reviewing related articles and combining the clinical experiences,the anatomic features(fat compartments and blood supply),aging features of the perioral and lower face,and the application advancement and related complications of autologous fat grafting in this area were generally summarized.Results The aesthetic features of perioral and lower face include the lip,chin,and so on,and the anatomic structures relating autologous fat grafting include the mandibular fat compartments,chin fat compartments,and other fat compartments.Meanwhile,the facial artery passes through this area and spreads out several important branches.The aging features of perioral and lower face include the depening of nasolabial fold,the aging lip,perioral wrinkles,“marionette lines”,and so on.Autologous fat grafting can improve perioral and lower face rejuvenation by restoring volume loss of facial fat compartments,correcting aging malformation,and improving skin quality.But there are neurovascular injuries,facial aesthetic problems,and other related complications.Conclusion Autologous fat grafting can be applied in perioral and lower face rejuvenation,and it can effectively improve related aging features.There are several aspects developing aggressively,including the research of facial asthetics features of Chinese people,combining autologous fat grafting with surgery as well as other methods to comprehensively treat facial aging,and the application of fat tissue related derivatives in perioral and lower face rejuvenation.However,the resorption rate of facial grafted fat tissue is still too high,and the long-term effectiveness can not be assured.In the future,the solutions related to improving the survival rate of grafted fat tissue need to be explored in the future.