A型肉毒毒素皮内注射治疗玫瑰痤疮持久性红斑及潮红专家共识

Expert consensus on intradermal injections with botulinum toxin A for the treatment of flushing and persistent erythema caused by rosacea

A型肉毒毒素是一种神经毒素,广泛用于皮肤美容。有证据表明,皮内注射A型肉毒毒素能改善玫瑰痤疮患者面部皮肤潮红及持续性红斑,但对治疗浓度、剂量、操作方法、疗程、治疗间隔等均存在差异。中华医学会皮肤性病学分会玫瑰痤疮研究中心、中国医师协会皮肤科分会玫瑰痤疮专业组在玫瑰痤疮诊疗指南的基础上,参考新近文献并结合诸多专家临床应用经验撰写本共识,为A型肉毒毒素皮内注射治疗玫瑰痤疮提供更科学、规范的参考依据。

Botulinum toxin A,a type of neurotoxin,is widely used in the field of cosmetic dermatology.Evidence has demonstrated that intradermal injections of botulinum toxin A can improve flushing and persistent erythema in patients with rosacea,while consensus on the treatment concentrations,doses,operation methods,courses,and intervals is still lacking.Based on guidelines for the diagnosis and treatment of rosacea,as well as recent literature and clinical experience of various experts,members of the Rosacea Research Center of Chinese Society of Dermatology and the Rosacea Professional Committee of China Dermatologist Association developed this consensus,aiming to provide scientific and standardized reference for the intradermal injections with botulinum toxin A in the treatment of rosacea.