呼吸内科住院患者喹诺酮类药物临床合理应用的药师药学干预效果分析

Analysis of the Effect of Pharmacist Pharmacy Intervention on the Clinical Rational Application of Quinolones in Inpatients of Respiratory Medicine

目的研究评价应用喹诺酮类药物治疗呼吸内科住院患者时,药师药学干预方案对促进临床用药合理性及临床效果的影响。方法选择2020年11—12月靖江市中医院呼吸内科住院的60例患者展开研究,按照随机数表法分为常规组和干预组,每组30例,常规组仅实施喹诺酮药物方案,不采取药师药学干预,干预组应用喹诺酮药物方案的同时,实施药师药学干预,针对组间临床效果及用药合理性进行讨论。结果干预组总有效率为96.67%高于常规组,差异有统计学意义(χ^(2)=4.706,P<0.05);干预组临床合理性(100.00%)优于常规组,差异有统计学意义(P<0.05);干预组不良反应发生率为13.33%低于常规组,差异有统计学意义(P<0.05)。结论药师药学干预方案,可促进呼吸内科住院患者用药合理性,提升临床疗效能够促使药物不良反应减少,临床效果提高。

Objective To study and evaluate the effect of pharmacist pharmacy intervention program on promoting the rational clinical use and clinical effect of quinolones in the application of quinolones in the treatment of inpatients in respiratory medicine.Methods A study was conducted on 60 patients hospitalized in the Department of Respiratory Medicine of Jingjiang Hospital of Traditional Chinese Medicine from November to December 2020,according to the random number table method,they divided into the conventional group and the intervention group,with 30patients in each group.In the conventional group,only the quinolone drug regimen was implemented without pharmacist pharmacy intervention,and in the intervention group,the quinolone drug regimen was applied along with pharmacist pharmacy intervention,and the clinical effects and rationality of medication use were discussed between the groups.Results The clinical efficacy rate(96.67%)of the intervention group was higher than that of the conventional group,and the difference was statistically significant(χ^(2)=4.706,P<0.05).The clinical rationality(100.00%)of the intervention groupwas better than that of the conventional group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions(13.33%)in the intervention group was lower than that in the conventional group,and the difference was statistically significant(P<0.05).Conclusion The pharmacist’s pharmaceutical intervention program can promote the rationality of drug use for inpatients in the respiratory department,improve the clinical efficacy,reduce adverse drug reactions,and improve the clinical efficacy.