经尿道前列腺电切术治疗前列腺增生合并前尿道狭窄的疗效及QOL评分影响评价

Effect of Transurethral Resection of Prostate on Benign Prostatic Hyperplasia with Anterior Urethral Stricture and Evaluation of QOL Scores

目的探讨前列腺增生合并前尿道狭窄患者经尿道前列腺电切术治疗的疗效及QOL评分。方法选取本院2018年10月-2020年10月收治的98例前列腺增生合并前尿道狭窄的患者为研究对象,在双方知情的前提下,通过双盲法将患者分为两组,其中列入对照组的患者采用传统开放手术治疗,另外列入观察组的患者经尿道前列腺电切术治疗,两组内各有49例患者。统计两组患者的术中出血量、术后留置尿管的时间、住院时间,同时将两组患者最大尿流量、残余尿流量进行比较,并对患者治疗前后的前列腺症状(IPSS)积分、生活质量评分(QOL)进行比较。结果对照组患者的术中失血量、术后尿管留置时间、住院时间均多于观察组患者,差异有统计学意义(P<0.05)。两组患者手术前的最大尿流量以及残余尿流量均不存在统计学差异性(P>0.05),两组患者手术后最大尿流量显著升高,残余尿流量显著降低,且观察组变化幅度大于对照组,差异有统计学意义(P<0.05);两组患者在手术前的IPSS评分、QOL评分均不存在显著的统计学差异性(P>0.05),两组患者手术后QOL评分显著提升,IPSS评分显著降低,且观察组QOL评分提升幅度大于对照组,IPSS评分降低程度也大于对照组患者,差异有统计学意义(P<0.05)。结论经尿道前列腺电切术作为治疗前列腺增生合并前尿道狭窄的经典术式,其可增加患者尿流量,减少其残余尿流量,促使其生活质量得以提升。

Objective To investigate effect and QOL scores of transurethral resection of prostate(TURP)for patients with benign prostatic hyperplasia(BPH)and anterior urethral stricture.Methods The paper chose 98 patients with benign prostatic hyperplasia and anterior urethral stricture admitted to our hospital from October 2018 to October 2020 as study subjects,and divided them into two groups with double blind method under premise of mutual knowledge.Control group was treated with traditional open surgery,and observation group with transurethral resection of prostate.There were 49 cases in each group.Intraoperative bleeding amount,time of indwelling catheter after operation,length of stay were counted between two groups.At the same time,maximum urine flow and residual urine flow between two groups was compared,scores of prostate symptoms(IPSS)and life quality(QOL)before and after treatment were compared.Results blood loss amount during operation,retention time of urinary tube after operation,length of stay in control group were longer than observation group,with statistically significant difference(P<0.05).There was no statistical difference between two groups in terms of maximum urine flow and residual urine flow before operation(P>0.05).Maximum urine flow after operation was significantly increased and residual urine flow was significantly decreased between two groups,change range in observation group was higher than control group,with statistically significant difference(P<0.05);There was no significant statistical difference between two groups in IPSS and QOL scores before surgery(P>0.05).After surgery,QOL scores of two groups increased significantly,while IPSS scores decreased significantly.QOL scores in observation group increased more than control group,and IPSS scores decreased more than control group,with statistically significant difference(P<0.05).Conclusion Transurethral resection of prostate(TURP),as classical operation for treatment of BPH with anterior urethral stricture,can increase urine flow,reduce residual urine flow,and promote life quality of patients.