摘要
目的 通过分析红花研究领域的英文文献,归纳红花研究热点,总结红花的药理活性,挖掘红花未来研究方向。方法 基于WebofScience数据库,运用CiteSpace5.8.R3软件通过检索平台收录2000—2021年红花相关研究的英文文献进行文献计量学分析,从机构发文量、国家发文量、作者发文量、Top20被引文献、Top15期刊发文量、关键词的共现以及未来热点等方面进行分析和可视化展现。结果 研究共纳入1 230篇文献,2007—2021年发文量占比89.5%,主要集中在亚洲国家,例如中国、伊朗以及印度等。发文机构主要集中在亚洲国家的高校,其中伊朗伊斯兰阿扎德大学为发文量最多的机构,多达53篇;在中国范围内形成了以中国科学院大学、北京大学等大学为核心的科研合作网络,是红花研究领域的密切合作机构。发文量最多的作者是以Meili Guo为代表的团队,该团队研究内容涉及红花以及其近缘种的遗传机制,发文量共计13篇。关键词分析显示研究方向集中在红花的种植、有效成分、药理机制、活化反应等方面,红花有效成分的抗氧化能力以及对阿尔茨海默病的治疗将成为未来的研究热点。结论 红花的年发文量呈逐年递增趋势,其未来的研究热点方向主要集中在发掘其有效成分新的药理作用以及疾病治疗效果的验证方面。对于红花的相关研究仍处于发展阶段,相关研究团队应加强跨区域合作,为后续红花的相关研究提供重要参考。
OBJECTIVE To summarize the research hotspots of Carthamus tinctorius L. by analyzing the English literature on Carthamus tinctorius L. and summarize the pharmacological activities of Carthamus tinctorius L.. To explore the future research direction of Carthamus tinctorius L.. METHODS Based on Web of Science database and CiteSpace 5.8.R3software, English literatures related to Carthamus tinctorius L. from 2000 to 2021 were collected on the retrieval platform for bibliometric analysis. Analysis and visualization were made from the number of articles published by the institutions, countries,authors, Top 20 cited literatures, Top15 journals, co-occurrence of keywords and future hot spots. RESULTS A total of 1 230articles were included in the study, accounting for 89.5% of the total number of articles published from 2007 to 2021, mainly in Asian countries, such as China, Iran and India, et al. The sending agencies were mainly concentrated in universities in Asian countries. Among them, Iran’s Islamic Azad University had the largest number of publications with 53. It had formed a research cooperation network with university of Chinese Academy of Sciences, Peking University and other universities as the core and had become a close cooperation institution in the field of Carthamus tinctorius L research in China. The authors with the largest number of papers was the team represented by Meili Guo. The research of the team involved the genetic mechanism of Carthamus tinctorius L. and its relatives with a total of 13 papers. Analysis of keywords showed that the research direction focused on the cultivation, active components, pharmacological mechanism and activation reaction of safflower, and the antioxidant capacity of the active components of Carthamus tinctorius L. and the treatment of Alzheimer’s disease would become hot research spots in the future. CONCLUSION The annual amount of Carthamus tinctorius L. is increasing year by year, its future research focuses on exploring new pharmacological effects of its active components and verifying the therapeutic effects of diseases. Relevant researches on Carthamus tinctorius L. are still in the development stage and relevant research teams should strengthen trans-regional cooperation to provide important reference for subsequent researches on Carthamus tinctorius L..
作者
白皓天
李娅兰
牛捷
张翔珂
杨婧
王锐
BAI Haotian;LI Yalan;NIU Jie;ZHANG Xiangke;YANG Jing;WANG Rui(Heilongjiang University of Chinese Medicine,a.College of Pharmacy,Ministry of Education,Harbin 150040,China;College of Basic Medical,Ministry of Education,Harbin 150040,China;Key Laboratory of Basic and Application Research of Beiyao,Ministry of Education,Harbin 150040,China)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2022年第23期3070-3078,共9页
Chinese Journal of Modern Applied Pharmacy
基金
国家自然科学基金项目(81603418)
黑龙江省省属本科高校中央支持地方高校改革发展项目(2020YQ05)
黑龙江中医药大学“优秀创新人才支持计划”科研项目(201208)。