1989年—2021年6月国内药品短缺研究可视化分析

Visualization Analysis of Drug Shortage Studies in China from 1989 to June 2021

目的 基于文献分析中国药品短缺问题的研究现状,探讨中国药品短缺原因及特点,为完善中国药品短缺应对措施提供参考。方法 检索中国知网、万方数据库和维普数据库中1989年—2021年6月中国药品短缺相关中文文献,利用可视化分析软件CiteSpace,对文献的发表时间、作者、研究机构、关键词,以及药品短缺原因等进行统计分析。结果 共有400篇文献纳入研究,中国药品短缺的研究文献数量从2011年起呈现出明显的增长趋势,作者和研究机构合作网络分散,研究团队以高校和研究所为主;关键词“药品供应链”“国家基本药物”政策以及“药品价格”方面是药品短缺领域的研究重点,“监测预警”是该领域新的研究趋势。结论 针对中国药品短缺问题研究的系统性尚需提高。现有研究文献提示,供应链中的生产环节是引起中国药品短缺的主要环节,药品价格是重要的影响因素,国家基本药物在短缺药品中占比较高,这些问题需要关注并值得进一步研究。

OBJECTIVE To analyze the present situation of the research on drug shortage in China based on the literature,the reasons and characteristics of drug shortage were described, so as to provide reference for improving the countermeasures of drug shortage in China. METHODS Chinese literatures related to drug shortage in China from 1989 to June 2021 were retrieved from CNKI, Wanfang database and VIP database. The visualized analysis software CiteSpace was used to statistically analyze the publication time, authors, research institutions and keywords of the obtained literatures, as well as the reasons for drug shortage. RESULTS A total of 400 articles were selected. The number of research documents on drug shortage in China had shown an obvious trend of growth since 2011, but the cooperative network between authors and research institutions was scattered, and the research teams were mainly universities and study institutes. Keywords “drug supply chain” “national essential medicine” and “drug price” were the research focus in the field of drug shortage, “monitoring and early warning” was the new trend in the field of drug shortage. CONCLUSION The systematic research on drug shortage in China need to be improved.Existing research literatures indicate that the production link in the supply chain is the main link causing drug shortage in China,drug price is an important factor, and national essential drugs account for a relatively high proportion in shortage drugs. These problems need to be paid attention and deserve further study.