氟对机体多系统的非骨相组织损害的研究进展

Research progress of fluoride on non-skeletal injury in multiple systems of the body

氟是人体必需微量元素, 适量氟可对机体产生一定的积极影响, 但人体长期摄入过量的氟会对机体造成损伤作用, 后者是地方性氟中毒的重要发病原因。氟中毒主要特征是对机体骨骼和牙齿的骨相损害。近年来, 氟对机体非骨相损害的研究日益受到学者们的重视。本文围绕氟对泌尿系统、消化系统、神经系统、循环系统、生殖系统、免疫系统等多个系统的非骨相损害进行了综述, 为除骨相损害以外的氟中毒相关研究提供参考。

Fluorine is an essential trace element for human body.Appropriate amount of fluorine can have a certain positive impact on the body,but long-term intake of excessive fluorine will cause damage to the body,which is an important cause of endemic fluorosis.The main feature of fluorosis is skeletal injury to the bones and teeth of the body.In recent years,the research of non-skeletal injury has been increasingly paid attention by research scholars.This paper summarized the non-skeletal injury of fluorine to urinary,digestive,nervous,circulatory,reproductive,immune systems and other systems,providing a reference for fluorosis-related studies other than skeletal injury.