昼夜节律在癌症患者心理康复应用中的研究进展

Research progress in circadian rhythms in the application of psychological rehabilitation of cancer patients

癌症患者的心理问题严重影响其治疗效果,有效进行癌症患者的心理康复对改善其生存结局和生活质量具有重要意义。昼夜节律是生物体进化过程中适应环境的结果,内源性时钟系统破坏或外界环境改变致使机体与环境失同步会引起昼夜节律紊乱。昼夜节律紊乱是癌症患者的常见现象,昼夜节律变化与癌症患者的心理问题密切相关。不少研究认为癌症患者的昼夜节律紊乱可能会通过多种机制直接或间接对其心理造成影响,而通过调节患者昼夜节律展开的针对性干预可能是促进癌症患者心理康复的重要手段。

The psychological distress of cancer patients seriously affects their therapeutic effects.Effective psychological rehabilitation of cancer patients significantly improves their survival chance and quality of life.Circadian rhythm results from adaptation to the environment during the organism’s evolution.When the endogenous clock system is disrupted or the external environment is changed,the body and the environment are out of synchronization,and the circadian rhythm will be disrupted.Circadian rhythm disorder is a common phenomenon in cancer patients,and the changes of circadian rhythm are closely related to their psychological distress.Many studies believe that the circadian rhythm disorder of cancer patients may directly or indirectly affect their psychology through various mechanisms,and targeted intervention by regulating the circadian rhythm of patients may be an essential means to promote the psychological rehabilitation.