体外光学质量测试设备评价IOL的光学性能

Evaluation of Optical Performance of IOL in Vitro by Optical Bench

目的:利用体外光学质量测试设备评价人工晶状体(IOL)的光学性能。方法:实验研究。使用光学质量测试设备OptiSpheric?IOL PROⅡ对IOL的光学性能进行体外检测。比较Vivinex、SN60WF和ZCB00的光谱透过率;比较Vivinex、A1-UV、SN60WF和ZCB00在不同程度偏心和倾斜状态下的调制传递函数(MTF);比较AT LISA tri、Diff-aAY、SBL-3、Symfony和ZCB00在最佳远、中和近视力下的美国空军分辨力测试图(USAF分辨力测试图)和MTF。数据采用单因素方差分析和独立样本t检验进行统计学分析。结果:蓝光滤过型IOL Vivinex和SN60WF较非蓝光滤过型IOL ZCB00可明显减少400~500 nm波长的蓝光透过。在400 nm附近波长范围内,Vivinex的光谱透过率小于SN60WF,差异有统计学意义(t=-15.65,P<0.001);在影响褪黑素分泌的480 nm附近波长范围内,Vivinex的光谱透过率大于SN60WF,差异有统计学意义(t=11.04,P<0.001)。当IOL偏心或者倾斜的程度相同时,100 lp/mm空间频率处的MTF值,Vivinex和A1-UV均大于ZCB00和SN60WF,差异均有统计学意义(均P<0.05)。最佳远视力焦点方面,单焦点非球面ZCB00的MTF值最高,USAF分辨力最佳;最佳中程视力焦点方面,景深延长型Symfony的MTF值最高,USAF分辨力最佳;最佳近视力焦点方面,衍射折射型多焦点Diff-aAY的MTF值最高,USAF分辨力最佳。当单焦点IOL离焦度数超过0.50 D时,其分辨物体细节的视觉质量下降将超过无离焦状态的多焦点IOL。结论:Vivinex和SN60WF的光谱透过率不同;Vivinex和A1-UV较ZCB00和SN60WF对偏心和倾斜的耐受性更高;不同类型的多焦点IOL在远、中、近视力焦点的光学质量不同。

Objective::To evaluate the optical performance of intraocular lens in vitro by optical bench.Methods::In this experimental study,the intraocular lens(IOL)with different optical performance was tested in vitro by optical bench OptiSpheric?IOL PROⅡ.The spectral transmittance of Vivinex,SN60WF and ZCB00 were compared.The modulation transfer function(MTF)under different degrees of decentration and tilt were compared for Vivinex,A1-UV,SN60WF and ZCB00.The USAF resolution test charts and MTF of AT LISA tri,Diff-aAY,SBL-3,Symfony and ZCB00 were compared at the best distance,intermediate and near focus.The data were analyzed by one-way ANOVA and independent sample t-test.Results::Compared with non-blue-light filtering IOL ZCB00,blue-light filtering IOL Vivinex and SN60WF could significantly reduce the blue light transmission at the wavelength of 400-500 nm.In the wavelength range around 400 nm,the spectral transmittance of Vivinex was less than SN60WF,the difference was statistically significant(t=-15.65,P<0.001);in the wavelength range around 480 nm affecting melatonin secretion,the spectral transmittance of Vivinex was greater than SN60WF,the difference was statistically significant(t=11.04,P<0.001).When the IOL was decentrated or tilt in the same extent,the MTF values at 100 lp/mm spatial frequency of Vivinex and A1-UV were better than ZCB00 and SN60WF,the difference was statistically significant(all P<0.05).The best distance focus,ZCB00 had the highest MTF value and the best USAF resolution;the best intermediate focus,Symfony had the highest MTF value and the best USAF resolution;the best near focus,Diff-aAy has the highest MTF value and the best USAF resolution.When the defocus degree of monofocal IOL exceeded 0.50 D,the visual quality of resolving object details would decline more than that of multifocus IOL without defocus.Conclusions::The spectral transmittance of Vivinex and SN60WF are different.Vivinex and A1-UV are more tolerant to decentration and tilt than ZCB00 and SN60WF.Different types of multifocal IOLs have different optical quality at the distance,intermediate and near focus.