舒更葡糖钠在胸腔镜肺结节切除术中的应用价值

Application Value of Sugammadex Sodium in Thoracoscopic Pulmonary Nodule Resection

目的:探讨舒更葡糖钠在胸腔镜肺结节切除术中的应用价值。方法:纳入2019年6月—2022年6月经无锡市第二人民医院收治行择期胸腔镜肺结节切除手术患者98例进行研究,采用随机数字表法分为新斯的明组(N组),舒更葡糖钠组(S组),每组49例。N组给予新斯的明和阿托品拮抗,S组给予舒更葡糖钠拮抗,比较两组术后肌松恢复情况、胃肠功能恢复情况及预后。结果:S组TOFr恢复至90%时间、拔管时间、肌松恢复指数短于N组,给予肌松拮抗药后15 min肌松残余率低于N组(P<0.05);S组首次排气时间、首次排便时间短于N组(P<0.05);S组入PACU未吸氧时SpO_(2)<93%占比、恶心呕吐发生率、PPCs发生率低于N组,PACU停留时间、住院天数短于N组,出恢复室Steward评分高于N组(P<0.05)。结论:应用舒更葡糖钠治疗胸腔镜肺结节切除术患者的肌松恢复效果良好,可促进胃肠功能恢复,改善预后。

Objective: To investigate the application value of sugammadex sodium in thoracoscopic pulmonary nodule resection. Methods: From June 2019 to June 2022,98 patients who underwent elective thoracoscopic pulmonary nodule resection in Wuxi Second People’s Hospital were included in the study. They were randomly divided into neostigmine group(group N) and sugammadex sodium group(group S), with 49 cases in each group. Group N was given neostigmine and atropine antagonism, and group S was given glucosamine sodium antagonism. The recovery of muscle relaxation, recovery of gastrointestinal function and prognosis were compared between the two groups. Results: The time of TOFr recovery to 90%,extubation time and muscle relaxation recovery index in group S were shorter than those in group N, and the residual rate of muscle relaxation 15 min after muscle relaxation antagonist was lower than that in group N(P<0.05). The first exhaust time and first defecation time in group S were shorter than those in group N(P<0.05). The proportion of SpO_(2)<93%, the incidence of nausea and vomiting, and the incidence of PPCs in group S were lower than those in group N when entering PACU without oxygen inhalation, the PACU stay time and hospitalization days were shorter than those in group N, and the Steward score in the recovery room was higher than that in group N(P<0.05). Conclusion: The application of sugammadex sodium in the treatment of thoracoscopic pulmonary nodule resection in patients with muscle recovery effect is good, which can promote the recovery of gastrointestinal function, improve the prognosis..