摘要
Infrared neuron stimulation is regarded as an innovative approach for stimulating cochleae in animals while the exact mechanism still remains unknown.In this paper,we studied compound action potentials of guinea pig cochleae with chronic or acute deafness.We recorded optical compound action potentials and analyzed stretched cochlear preparations by fiuorescence microscopy.Photoacoustic signals were measured by hydrophone and microphone,respectively.In our experiment,we observed a switch response effect in vitro and in vivo experiments.Therefore,we proposed photoacoustic effect could invoke auditory response in infrared neuron stimulation.
基金
This projectwas supported by grants fromtheNature Science Foundation of China(Nos.NSFC81401539 and NSFC31271056)and the projects in the Shenzhen Medical Engineering Laboratory For Human Auditory-equilibrium Function.