低水平激光用于加速正畸牙齿移动的研究进展

Advances in low-level laser therapy for the acceleration of orthodontic tooth movement

以往研究表明,低水平激光治疗(low-level laser therapy,LLLT)可能具有加速牙齿移动的效果。笔者通过查阅文献,总结归纳了LLLT在加速牙齿移动方面的临床效果及其生物学机制。大多数研究认为,LLLT可加速牙齿移动。但也有一些研究认为LLLT不具有加速正畸牙齿移动的效果。LLLT具有小剂量刺激,大剂量抑制的特点。因此,结果差异可能与激光应用时的参数设置有关。LLLT通过光生物调节作用,促进牙齿周围骨组织的改建。研究表明,接受LLLT的患者,牙周组织中的骨细胞数、局部胶原蛋白量、炎症因子的表达情况等均出现差异,但具体的机制尚不明确,有待更深入的研究。

Previous studies indicated that low-level therapy(LLLT) may accelerate tooth movement.We review literature to summarize the clinical effect of LLLT on accelerating tooth movement and its biological mechanism.A majority of the studies believed that LLLT could accelerate orthodontic tooth movement.However,some studies believed that LLLT had no effect on the acceleration of orthodontic tooth movement.LLLT is characterized by low dose stimulation and high dose inhibition.Therefore,the difference may be related to parameters in its application.LLLT promotes the reconstruction of alveolar bone by photobiomodulation.Results of recent research have showed that the number of bone cells,local collagen content and the expression of inflammatory factors in periodontal tissues of the patients treated with LLLT were regulated,but the biological mechanism remains to be discovered by further research.