富血小板血浆影响正畸牙齿移动效率的研究进展

Advances in studies on platelet-rich plasma affecting orthodontic tooth movement efficiency

富血小板血浆(PRP)是一种从自体血液中提取的血小板浓缩物,含有丰富的细胞因子和生长因子,其中血小板衍生生长因子、转化生长因子β、血管内皮生长因子主要对成骨细胞和破骨细胞的活性产生影响,促进骨重建过程。正畸牙的移动效率受到骨重建的影响,故局部注射PRP将是加速正畸牙齿移动效率的新方向。该文主要对PRP在正畸治疗中加速正畸牙移动效率的相关实验及其基础研究进行了综述,有助于进一步探讨PRP应用于临床治疗中加速正畸牙移动效率的可行性。

Platelet-rich plasma(PRP),a platelet concentrate derived from autologous blood,is rich in cytokines and growth factors.Among these factors,platelet-derived growth factor(PDGF),transforming growth factor β(TGF-β)and vascular endothelial growth factor(VEGF)mainly affect the activity of osteoblasts and osteoclasts,thus promoting the process of bone reconstruction.The efficiency of orthodontic teeth movement is influenced by bone reconstruction,so local injection of PRP will be a new direction to accelerate the efficiency of orthodontic teeth movement.This paper mainly reviews the application of PRP in orthodontic treatment to accelerate the efficiency of orthodontic teeth movement and relevant research,which will help further explore the feasibility of PRP in clinical treatment to accelerate the efficiency of orthodontic teeth movement.