摘要
Purpose:The aim of this paper was to examine the distribution of macular,retinal nerve fiber layer(RNFL)thickness and optic disc parameters of myopic and hyperopic eyes in comparison withemmetropic control eyes and to investigate their variation according to axial length(AL)andspherical equivalent(SE)in healthy children.Methods:This study included 293 pairs of eyes of 293children(145 boys and 148 girks),ranging in age from 6 to 17 years,Subjects were dividedaccording to SE in control(emmetropia,99 children),myopia(100 children)and hyperopia(94children)groups and according to axial AL in 68 short(<22.00 mm,68),medium(from≥22.00 mmto 25.00 mm,189)and long eyes(>25.00 mm,36).Macular parameters,RNFL thickness and opticdisc morphology were assessed by the Cirrus^(TM) HD-OCT.AL was measured using the IOL-Mastersystem.Littmann's formula was used for calculating the corrected AL-related ocular magnification.Results Mean age(±SD)was 10.84±3.05 years;mean(±SD)SE was+0.14±0.51 D(range from8.75 to+8.25 D)and mean AL(±SD)was 23.12±1.49.Average RNFL thickness,averagemacular thickness and macular volume decreased as AL and myopia increased.No correlationsbetween AL/SE and optic disc parameters were found after correcting for magnification effect.Conclusions:AL and refractive error affect measurements of macular and RNFL thickness inhealthy children.To make a correct interpretation of ocT measurements,ocular magnificationeffect should be taken into account by clinicians or OCT manufacturers.
